Abstract
Eye-head co-ordination of patients with Parkinsonism and cerebellar ataxia was investigated and compared with that of normal subjects. In Parkinsonian patients eye-head co-ordination was of the same pattern as normals, with an accurate and stable gaze. Reaction times for both eyes and head, however, were prolonged. It was also noted that the contribution of head movements to gaze shift was abnormally large and that the gaze accuracy was decreased when the head was immobilised. In patients with cerebellar ataxia, gaze was dysmetric, often hypermetric, and was unstable during head movements. The contribution of head movements to gaze was also large. It is concluded that Parkinsonism and cerebellar diseases influence eye-head co-ordination differently.
Full text
PDF






Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Aschoff J. C., Cohen B. Changes in saccadic eye movements produced by cerebellar cortical lesions. Exp Neurol. 1971 Aug;32(2):123–133. doi: 10.1016/0014-4886(71)90056-2. [DOI] [PubMed] [Google Scholar]
- Baloh R. W., Honrubia V., Sills A. Eye-tracking and optokinetic nystagmus. Results of quantitative testing in patients with well-defined nervous system lesions. Ann Otol Rhinol Laryngol. 1977 Jan-Feb;86(1 Pt 1):108–114. doi: 10.1177/000348947708600119. [DOI] [PubMed] [Google Scholar]
- Baloh R. W., Jenkins H. A., Honrubia V., Yee R. D., Lau C. G. Visual-vestibular interaction and cerebellar atrophy. Neurology. 1979 Jan;29(1):116–119. doi: 10.1212/wnl.29.1.116. [DOI] [PubMed] [Google Scholar]
- Baloh R. W., Konrad H. R., Honrubia V. Vestibulo-ocular function in patients with cerebellar atrophy. Neurology. 1975 Feb;25(2):160–168. doi: 10.1212/wnl.25.2.160. [DOI] [PubMed] [Google Scholar]
- Bartz A. E. Eye and head movements in peripheral vision: nature of compensatory eye movements. Science. 1966 Jun 17;152(3729):1644–1645. doi: 10.1126/science.152.3729.1644. [DOI] [PubMed] [Google Scholar]
- Bizzi E., Kalil R. E., Morasso P. Two modes of active eye-head coordination in monkeys. Brain Res. 1972 May 12;40(1):45–48. doi: 10.1016/0006-8993(72)90104-7. [DOI] [PubMed] [Google Scholar]
- Bizzi E., Kalil R. E., Tagliasco V. Eye-head coordination in monkeys: evidence for centrally patterned organization. Science. 1971 Jul 30;173(3995):452–454. doi: 10.1126/science.173.3995.452. [DOI] [PubMed] [Google Scholar]
- Corin M. S., Elizan T. S., Bender M. B. Oculomotor function in patients with Parkinson's disease. J Neurol Sci. 1972 Mar;15(3):251–265. doi: 10.1016/0022-510x(72)90068-8. [DOI] [PubMed] [Google Scholar]
- DeJong J. D., Jones G. M. Akinesia, hypokinesia, and bradykinesia in the oculomotor system of patients with Parkinson's disease. Exp Neurol. 1971 Jul;32(1):58–68. doi: 10.1016/0014-4886(71)90165-8. [DOI] [PubMed] [Google Scholar]
- Dichgans J., Bizzi E., Morasso P., Tagliasco V. Mechanisms underlying recovery of eye-head coordination following bilateral labyrinthectomy in monkeys. Exp Brain Res. 1973 Dec 20;18(5):548–562. doi: 10.1007/BF00234137. [DOI] [PubMed] [Google Scholar]
- Hassler R. Supranuclear structures regulating binocular eye and head movements. Bibl Ophthalmol. 1972;82:207–219. [PubMed] [Google Scholar]
- Highstein S., Cohen B., Mones R. Changes in saccadic eye movements of patients with Parkinson's disease before and after L-dopa. Trans Am Neurol Assoc. 1969;94:277–279. [PubMed] [Google Scholar]
- Jones G. M., DeJong J. D. Dynamic characteristics of saccadic eye movements in Parkinson's disease. Exp Neurol. 1971 Apr;31(1):17–31. doi: 10.1016/0014-4886(71)90173-7. [DOI] [PubMed] [Google Scholar]
- Miles F. A., Fuller J. H. Adaptive plasticity in the vestibulo-ocular responses of the rhesus monkey. Brain Res. 1974 Nov 22;80(3):512–516. doi: 10.1016/0006-8993(74)91035-x. [DOI] [PubMed] [Google Scholar]
- Ritchie L. Effects of cerebellar lesions on saccadic eye movements. J Neurophysiol. 1976 Nov;39(6):1246–1256. doi: 10.1152/jn.1976.39.6.1246. [DOI] [PubMed] [Google Scholar]
- Robinson D. A. Adaptive gain control of vestibuloocular reflex by the cerebellum. J Neurophysiol. 1976 Sep;39(5):954–969. doi: 10.1152/jn.1976.39.5.954. [DOI] [PubMed] [Google Scholar]
- Selhorst J. B., Stark L., Ochs A. L., Hoyt W. F. Disorders in cerebellar ocular motor control. I. Saccadic overshoot dysmetria. An oculographic, control system and clinico-anatomical analysis. Brain. 1976 Sep;99(3):497–508. doi: 10.1093/brain/99.3.497. [DOI] [PubMed] [Google Scholar]
- Shibasaki H., Tsuji S., Kuroiwa Y. Oculomotor abnormalities in Parkinson's disease. Arch Neurol. 1979 Jun;36(6):360–364. doi: 10.1001/archneur.1979.00500420070009. [DOI] [PubMed] [Google Scholar]
- Zee D. S., Yee R. D., Cogan D. G., Robinson D. A., Engel W. K. Ocular motor abnormalities in hereditary cerebellar ataxia. Brain. 1976 Jun;99(2):207–234. doi: 10.1093/brain/99.2.207. [DOI] [PubMed] [Google Scholar]
- Zee D. S., Yee R. D., Singer H. S. Congenital ocular motor apraxia. Brain. 1977 Sep;100(3):581–599. doi: 10.1093/brain/100.3.581. [DOI] [PubMed] [Google Scholar]
