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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Neurosurgery. 2016 Oct;79(4):568–577. doi: 10.1227/NEU.0000000000001183

Table 1.

Agreement between clustering and experts as quantified by Cohen's kappa for healthy controls and patients with brain tumors. Six tracts, namely the arcuate fasciculus (AF), the inferior fronto-occipital fasciculus (IFOF), the inferior longitudinal fasciculus (ILF), the cingulum bundle (CB), the fornix (FR), and the uncinate fasciculus (UF) were identified. Mean and standard deviation (in parentheses) are given. C: clustering, E1: expert 1, E2: expert 2, E: both experts (average of both). Intra-expert agreement quantifies the variation with the repeated drawings. The overall agreement between clustering and experts (C vs. E) is comparable to the agreement between experts (E1 vs. E2).

Healthy Controls Patients
Bundle C vs. E E1 vs. E2 E (Intra) C vs. E E1 vs. E2
IFOF 0.66 (0.05) 0.61 (0.08) 0.61 (0.14) 0.49 (0.21) 0.42 (0.22)
ILF 0.62 (0.09) 0.67 (0.04) 0.69 (0.10) 0.59 (0.17) 0.55 (0.20)
AF 0.64 (0.10) 0.46 (0.16) 0.78 (0.18) 0.46 (0.21) 0.49 (0.19)
UF 0.60 (0.13) 0.89 (0.03) 0.91 (0.05) N/A
CB 0.76 (0.05) 0.74 (0.05) 0.89 (0.04)
FR 0.61 (0.07) 0.59 (0.04) 0.83 (0.12)