Abstract
Ischaemic lesions along cerebral arterial boundary zones were present in nine patients dying after cardiopulmonary by-pass. Their intra-operative cerebral function monitor recordings had shown at least 7 min major depression, its severity correlating with degrees of neurological deficit after operation and EEG abnormality and extent of infarction. In contrast eleven patients with normal or minimally abnormal cerebral function monitor recordings had macroscopically normal brains.
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- BRIERLEY J. B. NEUROPATHOLOGICAL FINDINGS IN PATIENTS DYING AFTER OPEN-HEART SURGERY. Thorax. 1963 Dec;18:291–304. doi: 10.1136/thx.18.4.291. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Branthwaite M. A. Detection of neurological damage during open-heart surgery. Thorax. 1973 Jul;28(4):464–472. doi: 10.1136/thx.28.4.464. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Branthwaite M. A. Factors affecting cerebral activity during open-heart surgery. Anaesthesia. 1973 Nov;28(6):619–625. doi: 10.1111/j.1365-2044.1973.tb00545.x. [DOI] [PubMed] [Google Scholar]
- Branthwaite M. A. Prevention of neurological damage during open-heart surgery. Thorax. 1975 Jun;30(3):258–261. doi: 10.1136/thx.30.3.258. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Brierley J. B., Brown A. W., Excell B. J., Meldrum B. S. Brain damage in the rhesus monkey resulting from profound arterial hypotension. I. Its nature, distribution and general physiological correlates. Brain Res. 1969 Mar;13(1):68–100. doi: 10.1016/0006-8993(69)90144-9. [DOI] [PubMed] [Google Scholar]
- Brierley J. B., Prior P. F., Calverley J., Jackson S. J., Brown A. W. The pathogenesis of ischaemic neuronal damage along the cerebral arterial boundary zones in Papio anubis. Brain. 1980 Dec;103(4):929–965. doi: 10.1093/brain/103.4.929. [DOI] [PubMed] [Google Scholar]
- FISCHER-WILLIAMS M., COOPER R. A. SOME ASPECTS OF ELECTROENCEPHALOGRAPHIC CHANGES DURING OPEN-HEART SURGERY. Neurology. 1964 May;14:472–482. doi: 10.1212/wnl.14.5.472. [DOI] [PubMed] [Google Scholar]
- HARDEN A. EFFECTS OF ARTERIAL AND VENOUS PRESSURE CHANGES ON THE ELECTROENCEPHALOGRAM DURING CARDIAC OPERATIONS. Br Med J. 1965 Jan 2;1(5426):23–27. doi: 10.1136/bmj.1.5426.23. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Juneja I., Flynn R. E., Berger R. L. The arterial, venous pressures and the electroencephalogram during open heart sugery. Acta Neurol Scand. 1972;48(2):163–168. doi: 10.1111/j.1600-0404.1972.tb07537.x. [DOI] [PubMed] [Google Scholar]
- Maynard D., Prior P. F., Scott D. F. Device for continuous monitoring of cerebral activity in resuscitated patients. Br Med J. 1969 Nov 29;4(5682):545–546. doi: 10.1136/bmj.4.5682.545-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Morawetz R. B., Crowell R. H., DeGirolami U., Marcoux F. W., Jones T. H., Halsey J. H. Regional cerebral blood flow thresholds during cerebral ischemia. Fed Proc. 1979 Oct;38(11):2493–2494. [PubMed] [Google Scholar]
- ROMANUL F. C., ABRAMOWICZ A. CHANGES IN BRAIN AND PIAL VESSELS IN ARTERIAL BORDER ZONES; A STUDY OF 13 CASES. Arch Neurol. 1964 Jul;11:40–65. doi: 10.1001/archneur.1964.00460190044004. [DOI] [PubMed] [Google Scholar]
- Reilly E. L., Brunberg J. A., Doty D. B. The effect of deep hypothermia and total circulatory arrest on the electroencephalogram in children. Electroencephalogr Clin Neurophysiol. 1974 Jun;36(6):661–667. doi: 10.1016/0013-4694(74)90233-8. [DOI] [PubMed] [Google Scholar]
- Russell R. W., Bharucha N. The recognition and prevention of border zone cerebral ischaemia during cardiac surgery. Q J Med. 1978 Jul;47(187):303–323. [PubMed] [Google Scholar]
- Schwartz M. S., Colvin M. P., Prior P. F., Strunin L., Simpson B. R., Weaver E. J., Scott D. F. The cerebral function monitor. Its value in predicting the neurological outcome in patients undergoing cardiopulmonary by-pass. Anaesthesia. 1973 Nov;28(6):611–618. doi: 10.1111/j.1365-2044.1973.tb00544.x. [DOI] [PubMed] [Google Scholar]
- Schwartz M. S., Scott D. F. Pathological stimulus-related slow wave arousal responses in the EEG. Acta Neurol Scand. 1978 Apr;57(4):300–304. doi: 10.1111/j.1600-0404.1978.tb04504.x. [DOI] [PubMed] [Google Scholar]
- Sotaniemi K. A. Brain damage and neurological outcome after open-heart surgery. J Neurol Neurosurg Psychiatry. 1980 Feb;43(2):127–135. doi: 10.1136/jnnp.43.2.127. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wright J. S., Lethlean A. K., Hicks R. G., Torda T. A., Stacey R. Electroencephalographic studies during open-heart surgery. J Thorac Cardiovasc Surg. 1972 Apr;63(4):631–638. [PubMed] [Google Scholar]
- YATES P. O., HUTCHINSON E. C. Cerebral infarction: the role of stenosis of the extracranial cerebral arteries. Memo Med Res Counc. 1961;300:1–95. [PubMed] [Google Scholar]



