Skip to main content
NCBI home page
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1982 Apr;45(4):303–307. doi: 10.1136/jnnp.45.4.303

Evoked potentials in the diagnosis of multiple sclerosis: a follow up study.

W B Matthews, J R Wattam-Bell, E Pountney
PMCID: PMC491364  PMID: 7077339

Abstract

Visual, somatosensory and brain stem auditory evoked potentials were recorded in 84 patients in whom the diagnosis of multiple sclerosis was under consideration. The patients were followed up for a maximum of 38 months or until a definite diagnosis of multiple sclerosis or of some other condition was established. Seven patients were found not to have multiple sclerosis. Abnormal evoked potentials indicating clinically silent lesions were found at the initial investigation in fourteen of the twenty-eight patients in whom a diagnosis of clinically definite multiple sclerosis was accepted during the period of follow up. In the thirty-seven patients in whom no change in clinical category occurred during the period such abnormalities were found in five. The visual evoked potential was found to be of greatest predictive value.

Full text

PDF
303

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Beagley H. A., Sheldrake J. B. Differences in brainstem response latency with age and sex. Br J Audiol. 1978 Aug;12(3):69–77. doi: 10.3109/03005367809078858. [DOI] [PubMed] [Google Scholar]
  2. Clifford-Jones R. E., Clarke G. P., Mayles P. Crossed acoustic response combined with visual and somatosensory evoked responses in the diagnosis of multiple sclerosis. J Neurol Neurosurg Psychiatry. 1979 Aug;42(8):749–752. doi: 10.1136/jnnp.42.8.749. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Deltenre P., Vercruysse A., van Nechel C., Ketelaer P., Capon A., Colin F., Manil J. Early diagnosis of multiple sclerosis by combined multimodal evoked potentials: results and practical considerations. J Biomed Eng. 1979 Jan;1(1):17–21. doi: 10.1016/0141-5425(79)90006-2. [DOI] [PubMed] [Google Scholar]
  4. Green J. B., Price R., Woodbury S. G. Short-latency somatosensory evoked potentials in multiple sclerosis. Comparison with auditory and visual evoked potentials. Arch Neurol. 1980 Oct;37(10):630–633. doi: 10.1001/archneur.1980.00500590054007. [DOI] [PubMed] [Google Scholar]
  5. Halliday A. M., McDonald W. I., Mushin J. Visual evoked response in diagnosis of multiple sclerosis. Br Med J. 1973 Dec 15;4(5893):661–664. doi: 10.1136/bmj.4.5893.661. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Khoshbin S., Hallett M. Multimodality evoked potentials and blink reflex in multiple sclerosis. Neurology. 1981 Feb;31(2):138–144. doi: 10.1212/wnl.31.2.138. [DOI] [PubMed] [Google Scholar]
  7. Kjaer M. The value of brain stem auditory, visual and somatosensory evoked potentials and blink reflexes in the diagnosis of multiple sclerosis. Acta Neurol Scand. 1980 Oct;62(4):220–236. doi: 10.1111/j.1600-0404.1980.tb03029.x. [DOI] [PubMed] [Google Scholar]
  8. Mastaglia F. L., Black J. L., Collins D. W. Visual and spinal evoked potentials in diagnosis of multiple sclerosis. Br Med J. 1976 Sep 25;2(6038):732–732. doi: 10.1136/bmj.2.6038.732. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Matthews W. B., Esiri M. Multiple sclerosis plaque related to abnormal somatosensory evoked potentials. J Neurol Neurosurg Psychiatry. 1979 Oct;42(10):940–942. doi: 10.1136/jnnp.42.10.940. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Matthews W. B., Small D. G., Small M., Pountney E. Pattern reversal evoked visual potential in the diagnosis of multiple sclerosis. J Neurol Neurosurg Psychiatry. 1977 Oct;40(10):1009–1014. doi: 10.1136/jnnp.40.10.1009. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. McDonald W. I., Halliday A. M. Diagnosis and classification of multiple sclerosis. Br Med Bull. 1977 Jan;33(1):4–9. [PubMed] [Google Scholar]
  12. Paula-Barbosa M. M., Ruela C., Faria R., Cruz C. Cerebral cortex dendritic degeneration in subacute sclerosing panencephalitis (SSPE). Neurology. 1980 Jan;30(1):7–11. doi: 10.1212/wnl.30.1.7. [DOI] [PubMed] [Google Scholar]
  13. Purves S. J., Low M. D., Galloway J., Reeves B. A comparison of visual, brainstem auditory, and somatosensory evoked potentials in multiple sclerosis. Can J Neurol Sci. 1981 Feb;8(1):15–19. doi: 10.1017/s0317167100042773. [DOI] [PubMed] [Google Scholar]
  14. Robinson K., Rudge P. Abnormalities of the auditory evoked potentials in patients with multiple sclerosis. Brain. 1977 Mar;100(Pt 1):19–40. doi: 10.1093/brain/100.1.19. [DOI] [PubMed] [Google Scholar]
  15. Robinson K., Rudge P. The use of the auditory evoked potential in the diagnosis of multiple sclerosis. J Neurol Sci. 1980 Mar;45(2-3):235–244. doi: 10.1016/0022-510x(80)90168-9. [DOI] [PubMed] [Google Scholar]
  16. Small D. G., Matthews W. B., Small M. The cervical somatosensory evoked potential (SEP) in the diagnosis of multiple sclerosis. J Neurol Sci. 1978 Feb;35(2-3):211–224. doi: 10.1016/0022-510x(78)90004-7. [DOI] [PubMed] [Google Scholar]
  17. Trojaborg W., Petersen E. Visual and somatosensory evoked cortical potentials in multiple sclerosis. J Neurol Neurosurg Psychiatry. 1979 Apr;42(4):323–330. doi: 10.1136/jnnp.42.4.323. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES