Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(A) (i) Chemical structure of MLN-8237. (ii) IC-50 values of MLN-8237 in Sarcoma cell lines. IC-50s were determined by cell proliferation assay by using the Dojindo Cell Counting Kit done in six replicates. (B) (i) Dose curve for LS141 cells by clonogenic assay (averages of triplicates). (ii) Time-dose growth curve of LS141 as determined by colorimetric proliferation assay (average of six duplicates).
