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. 1975 Mar;38(3):219–224. doi: 10.1136/jnnp.38.3.219

Studies in man of phenytoin absorption and its implications.

F B Gibberd, M Webley
PMCID: PMC491899  PMID: 1151402

Abstract

The absorption of phenytoin was studied in man. It is concluded that phenytoin absorbed from the intestine is recirculated via the bile, so that blood levels do not accurately reflect absorption. Phenytoin is loosely bound to serum proteins and is found in red cells in concentrations similar to those in plasma. It is rapidly lost from the blood stream after intravenous administration, which is an important factor to be considered in the treatment of status epilepticus.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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