Skip to main content
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1975 Mar;38(3):279–287. doi: 10.1136/jnnp.38.3.279

Radiological abnormalities in temporal lobe epilepsy with clinicopathological correlations.

R L Newcombe, S H Shah
PMCID: PMC491909  PMID: 1080189

Abstract

In 73 patients with drug-resistant temporal lobe epilepsy submitted to an unilateral anterior temporal lobectomy the radiographs were studied to see if there were any correlation with the pathology subsequently found and with the outcome of the operation. A small middle cranial fossa, focal calcification, and temporal horn displacement are often better indices of the underlying pathology than temporal horn dilatation alone. In a small number of cases, however, radiological changes were seen on the side opposite to an unilateral EEG focus, thus suggesting bilateral disease.

Full text

PDF
279

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALEXANDER W. S. Cerebral calcification epilepsy; report of a case of epilepsy caused by a calcified hamartoma of the brain. J Neurosurg. 1953 Jan;10(1):69–74. doi: 10.3171/jns.1953.10.1.0069. [DOI] [PubMed] [Google Scholar]
  2. ALVORD E. C., Jr, BALDWIN M., VAN BUREN J. M. The temporal horn: its development, normal variations and changes associated with non-expanding epileptogenic lesions of the temporal lobe. Acta radiol. 1956 Dec;46(6):703–718. [PubMed] [Google Scholar]
  3. CAVANAGH J. B. On certain small tumours encountered in the temporal lobe. Brain. 1958 Sep;81(3):389–405. doi: 10.1093/brain/81.3.389. [DOI] [PubMed] [Google Scholar]
  4. FALCONER M. A., CAVANAGH J. B. Clinico-pathological considerations of temporal lobe epilepsy due to small focal lesions. A study of cases submitted to operation. Brain. 1959 Dec;82:483–504. doi: 10.1093/brain/82.4.483. [DOI] [PubMed] [Google Scholar]
  5. FALCONER M. A., KENNEDY W. A. Epilepsy due to small focal temporal lesions with bilateral independent spike-discharging foci. A study of seven cases relieved by operation. J Neurol Neurosurg Psychiatry. 1961 Aug;24:205–212. doi: 10.1136/jnnp.24.3.205. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. FALCONER M. A., POND D. A., MEYER A., WOOLF A. L. Temporal lobe epilepsy with personality and behaviour disorders caused by an unusual calcifying lesion; report of two cases in children relieved by temporal lobectomy. J Neurol Neurosurg Psychiatry. 1953 Nov;16(4):234–244. doi: 10.1136/jnnp.16.4.234. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. FALCONER M. A., SERAFETINIDES E. A., CORSELLIS J. A. ETIOLOGY AND PATHOGENESIS OF TEMPORAL LOBE EPILEPSY. Arch Neurol. 1964 Mar;10:233–248. doi: 10.1001/archneur.1964.00460150003001. [DOI] [PubMed] [Google Scholar]
  8. Falconer M. A. Problems in neurosurgery. Temporal lobe epilepsy. Trans Med Soc Lond. 1966;82:111–126. [PubMed] [Google Scholar]
  9. Falconer M. A. Significance of surgery for temporal lobe epilepsy in childhood and adolescence. J Neurosurg. 1970 Sep;33(3):233–252. doi: 10.3171/jns.1970.33.3.0233. [DOI] [PubMed] [Google Scholar]
  10. Falconer M. A., Taylor D. C. Surgical treatment of drug-resistant epilepsy due to mesial temporal sclerosis. Etiology and significance. Arch Neurol. 1968 Oct;19(4):353–361. doi: 10.1001/archneur.1968.00480040019001. [DOI] [PubMed] [Google Scholar]
  11. Falconer M. A. Temporal lobe epilepsy in children and its surgical treatment. Med J Aust. 1972 May 27;1(22):1117–1121. doi: 10.5694/j.1326-5377.1972.tb116602.x. [DOI] [PubMed] [Google Scholar]
  12. Fredy D., Bories J. A tomographic study of the temporal horn. Neuroradiology. 1972 Aug;4(2):96–107. doi: 10.1007/BF00344437. [DOI] [PubMed] [Google Scholar]
  13. KENNEDY W. A., HILL D. The surgical prognostic significance of the electroencephalographic prediction of Ammon's horn sclerosis in epileptics. J Neurol Neurosurg Psychiatry. 1958 Feb;21(1):24–30. doi: 10.1136/jnnp.21.1.24. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Margerison J. H., Corsellis J. A. Epilepsy and the temporal lobes. A clinical, electroencephalographic and neuropathological study of the brain in epilepsy, with particular reference to the temporal lobes. Brain. 1966 Sep;89(3):499–530. doi: 10.1093/brain/89.3.499. [DOI] [PubMed] [Google Scholar]
  15. Williams J. P., Slimack N. M., Fowler G. W. Radiographic hippocampal calcifications. Neuroradiology. 1972 Oct;4(3):159–161. doi: 10.1007/BF00327580. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES