Enhanced catecholamine secretion in Skn-1 KO mice fed a HFD.
(a) Serum triiodothyronine (T3), tetraiodothyronine (T4), and thyroid stimulating hormone (TSH) were comparable between Skn-1 KO and WT littermates (n = 7–8).
(b) Urinary epinephrine and dopamine were higher in Skn-1 KO mice than their WT littermates (n = 13–14). The data are presented as the mean ± SEM; *p < 0.05. See also Fig. S4.