Abstract
All five members of a family developed subacutely mental confusion and/or truncal ataxia. Symptoms and signs of polyneuropathy were seen later. The well water in the patients' home contained 400 ppm acrylamide. The present cases are unique in that they are cases of acrylamide poisoning induced by oral intake and percutaneous penetration, and that central nervous system symptoms were prominent.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Auld R. B., Bedwell S. F. Peripheral neuropathy with sympathetic overactivity from industrial contact with acrylamide. Can Med Assoc J. 1967 Mar 18;96(11):652–654. [PMC free article] [PubMed] [Google Scholar]
- BACHHUBER T. E., LALICH J. J., ANGEVINE D. M., SCHILLING E. D., STRONG F. M. Lathyrus factor activity of beta-aminopropionitrile and related compounds. Proc Soc Exp Biol Med. 1955 Jun;89(2):294–297. doi: 10.3181/00379727-89-21789. [DOI] [PubMed] [Google Scholar]
- Fullerton P. M., Barnes J. M. Peripheral neuropathy in rats produced by acrylamide. Br J Ind Med. 1966 Jul;23(3):210–221. doi: 10.1136/oem.23.3.210. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Garland T. O., Patterson M. W. Six cases of acrylamide poisoning. Br Med J. 1967 Oct 28;4(5572):134–138. doi: 10.1136/bmj.4.5572.134. [DOI] [PMC free article] [PubMed] [Google Scholar]
- KUPERMAN A. S. Effects of acrylamide on the central nervous system of the cat. J Pharmacol Exp Ther. 1958 Jul;123(3):180–192. [PubMed] [Google Scholar]
- Kaplan M. L., Murphy S. D. Effect of acrylamide on rotarod performance and sciatic nerve -glucuronidase activity of rats. Toxicol Appl Pharmacol. 1972 Jun;22(2):259–268. doi: 10.1016/0041-008x(72)90176-7. [DOI] [PubMed] [Google Scholar]
- MCCOLLISTER D. D., OYEN F., ROWE V. K. TOXICOLOGY OF ACRYLAMIDE. Ther Ggw. 1964 Mar;103:172–181. doi: 10.1016/0041-008x(64)90103-6. [DOI] [PubMed] [Google Scholar]