Abstract
Cutaneous afferent activity was recorded in fascicles of the median and radial nerves of normal subjects using percutaneous microelectrodes. Multi-unit fascicular responses were dominated by activity in large myelinated fibres. Easily tolerated electrical stimuli evoked the full spectrum of fast and slow myelinated fibre activity but more intense levels were required to activate unmyelinated fibres. Correlation of the evoked potentials and the sensations reported by the subject suggested that fast myelinated fibres mediate tactile sensations. Pricking pain appeared with the activation of slow myelinated fibres. The only sensations induced by electrical stimuli were tactile or painful.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Burke D., Skuse N. F., Lethlean A. K. Sensory function of the median nerve: preliminary studies using microelectrode techniques in man. Proc Aust Assoc Neurol. 1974;11:89–95. [PubMed] [Google Scholar]
- COLLINS W. R., Jr, NULSEN F. E., RANDT C. T. Relation of peripheral nerve fiber size and sensation in man. Arch Neurol. 1960 Oct;3:381–385. doi: 10.1001/archneur.1960.00450040031003. [DOI] [PubMed] [Google Scholar]
- Hagbarth K. E., Hongell A., Hallin R. G., Torebjörk H. E. Afferent impulses in median nerve fascicles evoked by tactile stimuli of the human hand. Brain Res. 1970 Dec 18;24(3):423–442. doi: 10.1016/0006-8993(70)90183-6. [DOI] [PubMed] [Google Scholar]
- Hallin R. G., Torebjörk H. E. Electrically induced A and C fibre responses in intact human skin nerves. Exp Brain Res. 1973 Jan 29;16(3):309–320. doi: 10.1007/BF00233333. [DOI] [PubMed] [Google Scholar]
- Mackenzie R. A., Burke D., Skuse N. F., Lethlean A. K. Fibre function and perception during cutaneous nerve block. J Neurol Neurosurg Psychiatry. 1975 Sep;38(9):865–873. doi: 10.1136/jnnp.38.9.865. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Torebjörk H. E., Hallin R. G. Identification of afferent C units in intact human skin nerves. Brain Res. 1974 Mar 8;67(3):387–403. doi: 10.1016/0006-8993(74)90489-2. [DOI] [PubMed] [Google Scholar]
- Torebjörk H. E., Hallin R. G. Perceptual changes accompanying controlled preferential blocking of A and C fibre responses in intact human skin nerves. Exp Brain Res. 1973 Jan 29;16(3):321–332. doi: 10.1007/BF00233334. [DOI] [PubMed] [Google Scholar]
- Vallbo A. B., Hagbarth K. E. Activity from skin mechanoreceptors recorded percutaneously in awake human subjects. Exp Neurol. 1968 Jul;21(3):270–289. doi: 10.1016/0014-4886(68)90041-1. [DOI] [PubMed] [Google Scholar]