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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Methods. 2016 Apr 25;103:99–119. doi: 10.1016/j.ymeth.2016.04.025

Figure 2.

Figure 2

Example of two loops with the same sequence forming different structures. The left panel shows an internal loop from E. coli making a S/R-like motif using an intercalated base, shown in blue. The right panel shows a loop with an identical sequence but without the intercalated base it forms a different structure.