Abstract
A patient is described in whom there was periodic deviation of the eyes in darkness associated with alternating nystagmus. An exactly similar situation occurs in normal man subjected to a pendular stimulus. It is proposed that in this patient there was alternating activity of the vestibular nuclei on either side of the brain-stem as a result of a removal of cerebellar inhibition, and that this caused periodic shifts in the null region of Daroff and Dell'Osso.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Brodal A. Organization of the commissural connections: anatomy. Prog Brain Res. 1972;37:167–176. doi: 10.1016/S0079-6123(08)63901-1. [DOI] [PubMed] [Google Scholar]
- Davis D. G., Smith J. L. Periodic alternating nystagmus. A report of eight cases. Am J Ophthalmol. 1971 Oct;72(4):757–762. doi: 10.1016/0002-9394(71)90014-6. [DOI] [PubMed] [Google Scholar]
- Dix M. R., Leech J. The use of infra-red light in the evaluation of vestibular disorders. J Laryngol Otol. 1974 Mar;88(3):199–206. doi: 10.1017/s0022215100078580. [DOI] [PubMed] [Google Scholar]
- Keane J. R. Periodic alternating nystagmus with downward beating nystagmus. A clinicoanatomical case study of multiple sclerosis. Arch Neurol. 1974 May;30(5):399–402. doi: 10.1001/archneur.1974.00490350057009. [DOI] [PubMed] [Google Scholar]
- Perkel D. H., Mulloney B. Motor pattern production in reciprocally inhibitory neurons exhibiting postinhibitory rebound. Science. 1974 Jul 12;185(4146):181–183. doi: 10.1126/science.185.4146.181. [DOI] [PubMed] [Google Scholar]
- Shimazu H. Organization of the commissural connections: physiology. Prog Brain Res. 1972;37:177–190. doi: 10.1016/S0079-6123(08)63902-3. [DOI] [PubMed] [Google Scholar]
- Towle P. A., Romanul F. Periodic alternating nystagmus: first pathologically studied case. Neurology. 1970 Apr;20(4):408–408. [PubMed] [Google Scholar]
- Trinder E. Instrument for the on-line measurement of the slow phase of nystagmus. Aviat Space Environ Med. 1975 Apr;46(4 SEC):441–444. [PubMed] [Google Scholar]
- Walberg F. Cerebellovestibular relations: anatomy. Prog Brain Res. 1972;37:361–376. doi: 10.1016/S0079-6123(08)63913-8. [DOI] [PubMed] [Google Scholar]