Skip to main content
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1976 Apr;39(4):314–319. doi: 10.1136/jnnp.39.4.314

Analysis of a case of periodic alternating nystagmus.

P Rudge, J Leech
PMCID: PMC492278  PMID: 932748

Abstract

A patient is described in whom there was periodic deviation of the eyes in darkness associated with alternating nystagmus. An exactly similar situation occurs in normal man subjected to a pendular stimulus. It is proposed that in this patient there was alternating activity of the vestibular nuclei on either side of the brain-stem as a result of a removal of cerebellar inhibition, and that this caused periodic shifts in the null region of Daroff and Dell'Osso.

Full text

PDF
314

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brodal A. Organization of the commissural connections: anatomy. Prog Brain Res. 1972;37:167–176. doi: 10.1016/S0079-6123(08)63901-1. [DOI] [PubMed] [Google Scholar]
  2. Davis D. G., Smith J. L. Periodic alternating nystagmus. A report of eight cases. Am J Ophthalmol. 1971 Oct;72(4):757–762. doi: 10.1016/0002-9394(71)90014-6. [DOI] [PubMed] [Google Scholar]
  3. Dix M. R., Leech J. The use of infra-red light in the evaluation of vestibular disorders. J Laryngol Otol. 1974 Mar;88(3):199–206. doi: 10.1017/s0022215100078580. [DOI] [PubMed] [Google Scholar]
  4. Keane J. R. Periodic alternating nystagmus with downward beating nystagmus. A clinicoanatomical case study of multiple sclerosis. Arch Neurol. 1974 May;30(5):399–402. doi: 10.1001/archneur.1974.00490350057009. [DOI] [PubMed] [Google Scholar]
  5. Perkel D. H., Mulloney B. Motor pattern production in reciprocally inhibitory neurons exhibiting postinhibitory rebound. Science. 1974 Jul 12;185(4146):181–183. doi: 10.1126/science.185.4146.181. [DOI] [PubMed] [Google Scholar]
  6. Shimazu H. Organization of the commissural connections: physiology. Prog Brain Res. 1972;37:177–190. doi: 10.1016/S0079-6123(08)63902-3. [DOI] [PubMed] [Google Scholar]
  7. Towle P. A., Romanul F. Periodic alternating nystagmus: first pathologically studied case. Neurology. 1970 Apr;20(4):408–408. [PubMed] [Google Scholar]
  8. Trinder E. Instrument for the on-line measurement of the slow phase of nystagmus. Aviat Space Environ Med. 1975 Apr;46(4 SEC):441–444. [PubMed] [Google Scholar]
  9. Walberg F. Cerebellovestibular relations: anatomy. Prog Brain Res. 1972;37:361–376. doi: 10.1016/S0079-6123(08)63913-8. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES