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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1976 Apr;39(4):325–329. doi: 10.1136/jnnp.39.4.325

Neuropsychiatric manifestations of infective endocarditis: a study of 95 patients at Ibadan, Nigeria.

O Bademosi, A O Falase, F Jaiyesimi, A Bademosi
PMCID: PMC492280  PMID: 932750

Abstract

Thirty-eight percent of patients with infective endocarditis (36 of 95) had neuropsychiatric manifestations. In 75% (27 of 36), these features were the major presenting picture. Fifteen patients (42%) presented with cerebrovascular lesions and seven (19%) with meningitis. Toxic encephalopathy (12.5%) was not uncommon. Other neurological syndromes seen included psychosis and spinal cord lesions. The mortality was high especially when the infective endocarditis was acute in onset. It is essential to search diligently for an underlying cardiac cause in patients who present with neuropsychiatric symptoms because treatment of the underlying pathology improves prognosis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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