Abstract
The symptoms of 100 patients with chronic cardiac sinoatrial disorder were analysed. The most common presenting features were syncope in 34 cases and dizziness in 22 cases. Over three-quarters of the patients had cerebral ischaemic symptoms at some stage of the disease. Diagnostic difficulties are often encountered and are illustrated by two case histories. Although sinoatrial disorder has been described in association with neuromuscular diseases, only one such example was found in this series. The patient had a limb girdle dystrophy with cardiomyopathy and diffuse disease of the cardiac conducting system. Muscle biopsy samples taken from 11 patients with idiopathic sinoatrial disorder were normal showing no evidence of subclinical muscular disease.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BLOOMFIELD D. A., SINCLAIR-SMITH B. C. PERSISTENT ATRIAL STANDSTILL. Am J Med. 1965 Aug;39:335–340. doi: 10.1016/0002-9343(65)90059-8. [DOI] [PubMed] [Google Scholar]
- Brownlee W. C., Evans R. C., Shaw D. B. Proceedings: Pathology of conducting system in sinoatrial disease. Br Heart J. 1975 Jul;37(7):779–779. [PubMed] [Google Scholar]
- Caponnetto S., Pastorini C., Tirelli G. Persistent atrial standstill in a patient affected with facioscapulohumeral dystrophy. Cardiologia. 1968;53(6):341–350. doi: 10.1159/000166205. [DOI] [PubMed] [Google Scholar]
- Davies M. J., Pomerance A. Quantitative study of ageing changes in the human sinoatrial node and internodal tracts. Br Heart J. 1972 Feb;34(2):150–152. doi: 10.1136/hrt.34.2.150. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HOLTER N. J. New method for heart studies. Science. 1961 Oct 20;134(3486):1214–1220. doi: 10.1126/science.134.3486.1214. [DOI] [PubMed] [Google Scholar]
- Lambert C. D., Fairfax A. J. Neurological associations of chronic heart block. J Neurol Neurosurg Psychiatry. 1976 Jun;39(6):571–575. doi: 10.1136/jnnp.39.6.571. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lippestad C. T., Marton P. F. Sinus arrest in proximal right coronary artery occlusion. Am Heart J. 1967 Oct;74(4):551–556. doi: 10.1016/0002-8703(67)90015-4. [DOI] [PubMed] [Google Scholar]
- Moss A. J., Davis R. J. Brady-Tachy syndrome. Prog Cardiovasc Dis. 1974 Mar-Apr;16(5):439–454. doi: 10.1016/0033-0620(74)90005-x. [DOI] [PubMed] [Google Scholar]
- Radford D. J., Julian D. G. Sick sinus syndrome: experience of a cardiac pacemaker clinic. Br Med J. 1974 Aug 24;3(5929):504–507. doi: 10.1136/bmj.3.5929.504. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rubenstein J. J., Schulman C. L., Yurchak P. M., DeSanctis R. W. Clinical spectrum of the sick sinus syndrome. Circulation. 1972 Jul;46(1):5–13. doi: 10.1161/01.cir.46.1.5. [DOI] [PubMed] [Google Scholar]
- SHORT D. S. The syndrome of alternating bradycardia and tachycardia. Br Heart J. 1954 Apr;16(2):208–214. doi: 10.1136/hrt.16.2.208. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Schwartz P. J., Periti M., Malliani A. The long Q-T syndrome. Am Heart J. 1975 Mar;89(3):378–390. doi: 10.1016/0002-8703(75)90089-7. [DOI] [PubMed] [Google Scholar]
- Spellberg R. D. Familial sinus node disease. Chest. 1971 Sep;60(3):246–251. doi: 10.1378/chest.60.3.246. [DOI] [PubMed] [Google Scholar]
- Thomas P. K., Calne D. B., Elliott C. F. X-linked scapuloperoneal syndrome. J Neurol Neurosurg Psychiatry. 1972 Apr;35(2):208–215. doi: 10.1136/jnnp.35.2.208. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Van Durme J. P. Tachyarrhythmias and transient cerebral ischemic attacks. Am Heart J. 1975 Apr;89(4):538–540. doi: 10.1016/0002-8703(75)90164-7. [DOI] [PubMed] [Google Scholar]