BMDM derived from WT or miR-223 KO animals were treated with IL-4 for 6 days and then stained with Giemsa and May Grunwald (A). Number of FBGC per field of view, nuclei/FBGC, and percent fusion were assayed (B). WT and miR-223 KO mice were implanted SC with Millipore filters for four weeks. Implants were removed, stained with Masson’s Trichrome to visualize FGBC and capsule (C). Number of FBGC per high power field and capsule thickness were quantified using Image J software (D). Scale bar = 50um,* indicates p-value <0.05, N=3.