Table 1. Univariate and multivariate analysis of prognostic factors for DMFS in 449 patients with NPC.
| Variable | Univariate analysis | Multivariate analysis | |
|---|---|---|---|
| P-value | HR (95% CI) | P–value a | |
| Age | 0.067 | - | 0.196 |
| Gender | 0.667 | 0.994 | |
| Pathologyb (Keratinizing squamous cell carcinoma vs. Non-keratinizing carcinoma) |
0.484 | - | 0.968 |
| Tc (T1-2 vs. T3-4) | 0.033 | - | 0.155 |
| Nc (N0-1 vs. N2-3) | <0.001 | - | 0.576 |
| RPA group | <0.001 | 3.090(1.975-4.835) | <0.001 |
| Chemotherapy | 0.279 | - | 0.920 |
Abbreviations: NPC = nasopharyngeal carcinoma; HR = hazard ratio; CI = confidence interval; T = tumour; N = node; RPA = recursive partitioning analysis.
a
P-values were calculated using an adjusted Cox proportional hazards model.
b
Pathological type according to the 2005 World Health Organization classification of tumours.
c
According to the 7th UICC/AJCC staging system.