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. 2016 Feb 13;7(12):13965–13975. doi: 10.18632/oncotarget.7369

Figure 4. 1 reactivates p53 transcriptional transactivation and induced apoptosis in cells.

Figure 4

1 induces (A) p53-driven luciferase activity, (B) the expression of endogenous p53 targets GADD45α and PUMA, (C) DNA fragmentation, (D) p21 expression, and (E) caspase-3/7 activities in A375 cells.