Table 3. LncRNAs significantly deregulated in MM patients with del13, del17 or 1q gain.
| lncRNA | Score(d) | Fold Change | Chr | ALIAS; OVERLAPPING TRANSCRIPTa | Corr. lncRNA-overlapping transcriptb | PsGc | Putative Parental Gene | Corr. lncRNA- parental geneb |
|---|---|---|---|---|---|---|---|---|
| del17 | ||||||||
| MEF2C-2 | 4.98 | 2.26 | 5q14 | LINC00461; S to MIR9-2 | NA | |||
| TRPV4-1 | 4.04 | 2.16 | 12q24 | FAM222A-AS1; AS to FAM222A | R= − 0.07 | |||
| ROPN1B-7 | 3.62 | 1.60 | 3q21 | FAM86JP | PP | FAM86C1 (11q13) | R= 0.22 | |
| 1q gain | ||||||||
| TOR1AIP2-5 | 3.81 | 1.48 | 1q25 | |||||
| ANGPTL1-3 | 3.78 | 1.38 | 1q25 | AS to RALGPS2 | R=0.3 p=3.8e-08 |
|||
| CD46-4 | 3.43 | 1.30 | 1q32 | AS to miR-102 | NA | |||
| SERPINC1-1 | 3.24 | 1.38 | 1q25 | GAS5; AS to ZBTB37 | R= 0.29 p=1.1e-06 | |||
| HNRNPU-1 | 3.12 | 1.48 | 1q44 | HNRNPU-AS1; AS to COX20 | R= 0.18 | |||
| TRAF5-1 | 3.11 | 1.35 | 1q32 | LINC00467 | ||||
| ANKRD36BP1-1 | 2.90 | 1.30 | 1q24 | ANKRD36BP1 | ||||
| del13 | ||||||||
| NEK3-1 | −4.07 | 0.70 | 13q14 | MRPS31P5 | UnP | NA | ||
| FAM60A-6 | −3.95 | 0.68 | 12p11 | S to OVOS2 | NA | |||
| FAM70B-1 | −3.67 | 0.79 | 13q14 | GAS6-AS1; AS to GAS6 | R= − 0.28 | |||
| CYorf15A.1-2 | −3.30 | 0.39 | Yq11 | TXLNG2P | UnP | TXLNG (Xp22) | R= − 0.07 | |
| MTRNR2L1-4 | −3.28 | 0.85 | 17p11 | PP | MT-ND2 | NA | ||
| ZFYVE1-4 | −3.03 | 0.87 | 14q24 | RN7SL586P | M | RN7SL (14q21) | NA | |
| RNASEH1-7 | −2.96 | 0.81 | 2p25 | TMSB4XP2; AS to COLEC11 | R= 0.19 | UnP | TMSB4X (Xp22) | NA |
| KDM5D-3 | −2.91 | 0.66 | Yq11 | |||||
| SLC7A1-1 | −2.81 | 0.82 | 13q12 | MTUS2-AS1; AS to MTUS2 | R= 0.19 | |||
| SPRYD7-1 | −2.70 | 0.72 | 13q14 | DLEU2; AS to TRIM13 | R= 0.09 | |||
| RCOR3-1 | −2.67 | 0.87 | 1q32 | PP | RPS25 (11q23) | NA | ||
| BACH1-2 | −2.67 | 0.84 | 21q21 | GRIK1-AS1, AS to GRIK1 | R= 0.18 | |||
| CLYBL-1 | −2.65 | 0.76 | 13q32 | S to CLYBL | R= 0.24 | |||
| POM121L2-2 | 3.77 | 1.80 | 6p22 | ZNF204P | PP | NA |
a
Sense (S) to, or Antisense (AS) to overlapping transcripts
b
Pearson correlation coefficient; NA =not available (not detected by the array);
c
PsG=Pseudogene; Ensembl type: PP= Processed Pseudogene; UP= Unitary Pseudogene; UnP= Unprocessed Pseudogene; M= miscellaneous RNA.