Skip to main content
NCBI home page
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1977 Feb;40(2):149–155. doi: 10.1136/jnnp.40.2.149

Acute ascending polyradiculoneuritis in a case of Creutzfeldt-Jakob disease.

E S Lope, S R Junquera, A M Martinez, A B Berenguel
PMCID: PMC492630  PMID: 325182

Abstract

A patient is described who showed subacute dementia and ataxia and, finally, acute asending polyradiculoneuritis. At necropsy, together with the cerebral and cerebellar lesions that are typical of Creutzfeldt-Jakob disease, the lesions of the spinal motor neurons, the spinal ganglia, and of the roots and peripheral nerves were analogous with those of the Guillain-Barré-Landry syndrome. The aetiological possibility is discussed either that this is a simple and unique association, or that the disorder is related to the virus nature of Creutzfeldt-Jakob disease.

Full text

PDF
149

Images in this article

151Image
on p.151
152Image
on p.152
152Image
on p.152
153Image
on p.153
153Image
on p.153
154Image
on p.154
154Image
on p.154

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Abramsky O., Webb C., Teitelbaum D., Arnon R. Cell-mediated immunity to neural antigens in idiopathic polyneuritis and myeloradiculitis. Clinical-immunologic classification of several autoimmune demyelinating disorders. Neurology. 1975 Dec;25(12):1154–1159. doi: 10.1212/wnl.25.12.1154. [DOI] [PubMed] [Google Scholar]
  2. Allen I. V., Dermott E., Connolly J. H., Hurwitz L. J. A study of a patient with the amyotrophic form of Creutzfeldt-Jakob disease. Brain. 1971;94(4):715–724. doi: 10.1093/brain/94.4.715. [DOI] [PubMed] [Google Scholar]
  3. BROWNELL B., OPPENHEIMER D. R. AN ATAXIC FORM OF SUBACUTE PRESENILE POLIOENCEPHALOPATHY (CREUTZFELDT-JAKOB DISEASE). J Neurol Neurosurg Psychiatry. 1965 Aug;28:350–361. doi: 10.1136/jnnp.28.4.350. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Brion S., Mikol J., Raverdy P., Isidor P. Etude anatomo-clinique d'un cas de maladie de Creutzfeldt-Jakob. Aspects ultra-structuraux. Rev Neurol (Paris) 1969 Aug;121(2):165–179. [PubMed] [Google Scholar]
  5. Croft P. B., Urich H., Wilkinson M. Peripheral neuropathy of sensorimotor type associated with malignant disease. Brain. 1967 Mar;90(1):31–66. doi: 10.1093/brain/90.1.31. [DOI] [PubMed] [Google Scholar]
  6. Faris A. A., Martinez A. J. Primary progressive multifocal leukoencephalopathy. A central nervous system disease caused by a slow virus. Arch Neurol. 1972 Oct;27(4):357–360. doi: 10.1001/archneur.1972.00490160085012. [DOI] [PubMed] [Google Scholar]
  7. Gibbs C. J., Jr, Gajdusek D. C., Asher D. M., Alpers M. P., Beck E., Daniel P. M., Matthews W. B. Creutzfeldt-Jakob disease (spongiform encephalopathy): transmission to the chimpanzee. Science. 1968 Jul 26;161(3839):388–389. doi: 10.1126/science.161.3839.388. [DOI] [PubMed] [Google Scholar]
  8. Gomori A. J., Partnow M. J., Horoupian D. S., Hirano A. The ataxic form of Creutzfeldt-Jakob disease. Arch Neurol. 1973 Nov;29(5):318–323. doi: 10.1001/archneur.1973.00490290058006. [DOI] [PubMed] [Google Scholar]
  9. Hirano A., Ghatak N. R., Johnson A. B., Partnow M. J., Gomori A. J. Argentophilic plaques in Creutzfeldt-Jakob disease. Arch Neurol. 1972 Jun;26(6):530–542. doi: 10.1001/archneur.1972.00490120070008. [DOI] [PubMed] [Google Scholar]
  10. Jellinger K., Heiss W. D., Deisenhammer E. The ataxic (cerebellar) form of Creutzfeldt-Jakob disease. J Neurol. 1974;207(4):289–305. doi: 10.1007/BF00312583. [DOI] [PubMed] [Google Scholar]
  11. Langston J. W., Dorfman L. J., Forno L. S. "Encephalomyeloneuritis" in the absence of cancer. Neurology. 1975 Jul;25(7):633–637. doi: 10.1212/wnl.25.7.633. [DOI] [PubMed] [Google Scholar]
  12. Link H. Demonstration of oligoclonal immunoglobulin G IN Guillain-Barré syndrome. Acta Neurol Scand. 1975 Aug;52(2):111–120. doi: 10.1111/j.1600-0404.1975.tb05765.x. [DOI] [PubMed] [Google Scholar]
  13. May W. W. Creutzfeldt-Jakob disease. 1. Survey of the literature and clinical diagnosis. Acta Neurol Scand. 1968;44(1):1–32. doi: 10.1111/j.1600-0404.1968.tb07440.x. [DOI] [PubMed] [Google Scholar]
  14. Narayan O., Penney J. B., Jr, Johnson R. T., Herndon R. M., Weiner L. P. Etiology of progressive multifocal leukoencephalopathy. Identification of papovavirus. N Engl J Med. 1973 Dec 13;289(24):1278–1282. doi: 10.1056/NEJM197312132892405. [DOI] [PubMed] [Google Scholar]
  15. Roos R., Gajdusek D. C., Gibbs C. J., Jr The clinical characteristics of transmissible Creutzfeldt-Jakob disease. Brain. 1973;96(1):1–20. doi: 10.1093/brain/96.1.1. [DOI] [PubMed] [Google Scholar]
  16. Sheremata W., Colby S., Lusky G., Cosgrove J. B. Cellular hypersensitization to peripheral nervous antigens in the Guillain-Barré syndrome. Neurology. 1975 Sep;25(9):833–839. doi: 10.1212/wnl.25.9.833. [DOI] [PubMed] [Google Scholar]
  17. Sponzilli E. E., Smith J. K., Malamud N., McCulloch J. R. Progressive multifocal leukoencephalopathy: a complication of immunosuppressive treatment. Neurology. 1975 Jul;25(7):664–668. doi: 10.1212/wnl.25.7.664. [DOI] [PubMed] [Google Scholar]
  18. Vick N., Schulman S., Dau P. Carcinomatous cerebellar degeneration, encephalomyelitis, and sensory neuropathy (radiculitis). Report of a case incorporating both purely degenerative and intense inflammatory changes, with special prominence of the latter in the putamen. Neurology. 1969 May;19(5):425–441. doi: 10.1212/wnl.19.5.425. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES