Abstract
Plasma adrenaline and noradrenaline concentrations were measured in 21 patients after subarachnoid haemorrhage and in 13 control patients. Plasma noradrenaline concentrations were significantly raised in patients recovering from subarachnoid haemorrhage, confirming clinical evidence of overactivity of the sympathetic nervous system. Plasma noradrenaline concentrations in patients with a poor result were significantly higher at the time of admission than in patients with a good result, and the differences became more significant two to three days later. Therefore, the measurement of plasma noradrenaline concentrations may be a valuable test to assist clinical assessment in distinguishing between the two groups preoperatively.
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Selected References
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- Hörtnagl H., Benedict C. R., Grahame-Smith D. G. A sensitive radioenzymatic assay for adrenaline and noradrenaline in plasma. Br J Clin Pharmacol. 1977 Oct;4(5):553–558. doi: 10.1111/j.1365-2125.1977.tb00785.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Loach A. B., Azevedo Filho H. R. Some observations on the microneurosurgical treatment of intracranial aneurysms. Acta Neurochir (Wien) 1976;35(1-3):97–103. doi: 10.1007/BF01405938. [DOI] [PubMed] [Google Scholar]
- MELVILLE K. I., BLUM B., SHISTER H. E., SILVER M. D. CARDIAC ISCHEMIC CHANGES AND ARRHYTHMIAS INDUCED BY HYPOTHALAMIC STIMULATION. Am J Cardiol. 1963 Dec;12:781–791. doi: 10.1016/0002-9149(63)90281-9. [DOI] [PubMed] [Google Scholar]
- Mathias C. J., Christensen N. J., Corbett J. L., Frankel H. L., Spalding J. M. Plasma catecholamines during paroxysmal neurogenic hypertension in quadriplegic man. Circ Res. 1976 Aug;39(2):204–208. doi: 10.1161/01.res.39.2.204. [DOI] [PubMed] [Google Scholar]
- SMITH R. P., TOMLINSON B. E. Subendocardial haemorrhages associated with intracranial lesions. J Pathol Bacteriol. 1954 Oct;68(2):327–334. doi: 10.1002/path.1700680204. [DOI] [PubMed] [Google Scholar]
- SZAKACS J. E., MEHLMAN B. Pathologic changes induced by 1-norepineprine: quantitative aspects. Am J Cardiol. 1960 May;5:619–627. doi: 10.1016/0002-9149(60)90127-2. [DOI] [PubMed] [Google Scholar]
- VON EULERU QUANTITATION OF STRESS BY CATECHOLAMINE ANALYSIS. Clin Pharmacol Ther. 1964 Jul-Aug;5:398–404. doi: 10.1002/cpt196454398. [DOI] [PubMed] [Google Scholar]
- Weintraub B. M., McHenry L. C., Jr Cardiac abnormalities in subarachnoid hemorrhage: a resumé. Stroke. 1974 May-Jun;5(3):384–392. doi: 10.1161/01.str.5.3.384. [DOI] [PubMed] [Google Scholar]