Abstract
Three patients with peripheral neuropathy and a solitary plasmacytoma are presented, and the literature is reviewed. It is suggested that middle-aged men with an obscure progressive sensorimotor neuropathy, a raised CSF protein, and otherwise negative investigations should have a full skeletal survey since irradiation of a plasmacytoma may lead to a considerable improvement in the associated neurological disability.
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- AGUAYO A., THOMPSON D. W., HUMPHREY J. G. MULTIPLE MYELOMA WITH POLYNEUROPATHY AND OSTEOSCLEROTIC LESIONS. J Neurol Neurosurg Psychiatry. 1964 Dec;27:562–566. doi: 10.1136/jnnp.27.6.562. [DOI] [PMC free article] [PubMed] [Google Scholar]
- CROW R. S. Peripheral neuritis in myelomatosis. Br Med J. 1956 Oct 6;2(4996):802–804. doi: 10.1136/bmj.2.4996.802. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Currie S., Henson R. A., Morgan H. G., Poole A. J. The incidence of the non-metastatic neurological syndromes of obscure origin in the reticuloses. Brain. 1970;93(3):629–640. doi: 10.1093/brain/93.3.629. [DOI] [PubMed] [Google Scholar]
- Davidson S. Solitary myeloma with peripheral polyneuropathy--recovery after treatment. Calif Med. 1972 Jan;116(1):68–71. [PMC free article] [PubMed] [Google Scholar]
- Davis L. E., Drachman D. B. Myeloma neuropathy. Successful treatment of two patients and review of cases. Arch Neurol. 1972 Dec;27(6):507–511. doi: 10.1001/archneur.1972.00490180043010. [DOI] [PubMed] [Google Scholar]
- Getaz P., Handler L., Jacobs P., Tunley I. Osteosclerotic myeloma with peripheral neuropathy. S Afr Med J. 1974 Jun 15;48(29):1246–1250. [PubMed] [Google Scholar]
- Hesselvik M. Neuropathological studies on myelomatosis. Acta Neurol Scand. 1969;45(1):95–108. doi: 10.1111/j.1600-0404.1969.tb01223.x. [DOI] [PubMed] [Google Scholar]
- Mathews J. W., Jr, Olivier C. A. Osteoblastic multiple myeloma. South Med J. 1974 Mar;67(3):318–passim. doi: 10.1097/00007611-197403000-00018. [DOI] [PubMed] [Google Scholar]
- Morley J. B., Schwieger A. C. The relation between chronic polyneuropathy and osteosclerotic myeloma. J Neurol Neurosurg Psychiatry. 1967 Oct;30(5):432–442. doi: 10.1136/jnnp.30.5.432. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rushton D. I. Peripheral Sensorimotor Neuropathy Associated with a Localized Myeloma. Br Med J. 1965 Jul 24;2(5455):203–205. doi: 10.1136/bmj.2.5455.203. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SILVERSTEIN A., DONIGER D. E. NEUROLOGIC COMPLICATIONS OF MYELOMATOSIS. Arch Neurol. 1963 Nov;9:534–544. doi: 10.1001/archneur.1963.00460110102011. [DOI] [PubMed] [Google Scholar]
- VICTOR M., BANKER B. Q., ADAMS R. D. The neuropathy of multiple myeloma. J Neurol Neurosurg Psychiatry. 1958 May;21(2):73–88. doi: 10.1136/jnnp.21.2.73. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Walsh J. C. The neuropathy of multiple myeloma. An electrophysiological and histological study. Arch Neurol. 1971 Nov;25(5):404–414. doi: 10.1001/archneur.1971.00490050038003. [DOI] [PubMed] [Google Scholar]





