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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1978 Mar;41(3):272–277. doi: 10.1136/jnnp.41.3.272

Electroencephalography and phenytoin toxicity in mentally retarded epileptic patients.

M Iivanainen, M Viukari, A M Seppäläinen, E P Helle
PMCID: PMC493006  PMID: 632825

Abstract

There were significantly more diffuse and focal electroencephalographic abnormalities in 127 mentally retarded epileptic patients treated with phenytoin than in 68 epileptics without phenytoin. Phenytoin intoxication made the difference still more pronounced. Monitoring drug levels and electroencephalograms appears to be the method of choice for ensuring safe and effective medication in intractable epilepsy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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