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. 1978 Jun;41(6):516–524. doi: 10.1136/jnnp.41.6.516

Chronic brainstem encephalitis with mental symptoms and ataxia: report of three cases with necropsy.

T Ueno, N Takahata
PMCID: PMC493079  PMID: 671063

Abstract

Three necropsied cases of chronic, sporadic brainstem encephalitis of unknown aetiology are presented. Since their outstanding symptoms were dementia and ataxia of a progressive nature, a noninflammatory disease of the central nervous system was suspected. Neuropathological studies showed chronic inflammatory changes mainly in the brainstem without the presence of inclusion bodies or viral particles. Compared to cases previously reported as brainstem encephalitis, the clinical and pathological findings observed in these cases have rather peculiar characteristics.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BICKERSTAFF E. R. Brain-stem encephalitis; further observations on a grave syndrome with benign prognosis. Br Med J. 1957 Jun 15;1(5032):1384–1387. doi: 10.1136/bmj.1.5032.1384. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Boudouresques J., Toga M., Khalil R., Vigouroux R. A., Gosset A., Gastaut J. L. Encéphalite chronique. Prédominance des lésions sur les noyaux striés et le tronc cérébral. Etude anatomo-clinique. Discussion étiologique. Rev Neurol (Paris) 1969 May;120(5):336–345. [PubMed] [Google Scholar]
  3. Croft P. B., Henson R. A., Urich H., Wilkinson P. C. Sensory neuropathy with bronchial carcinoma: a study of four cases showing serological abnormalities. Brain. 1965 Sep;88(3):501–514. doi: 10.1093/brain/88.3.501. [DOI] [PubMed] [Google Scholar]
  4. Gluszcz A. Atypical encephalitis of the brain stem. Neuropatol Pol. 1966;4(Suppl):705–707. [PubMed] [Google Scholar]
  5. Henson R. A., Hoffman H. L., Urich H. Encephalomyelitis with carcinoma. Brain. 1965 Sep;88(3):449–464. doi: 10.1093/brain/88.3.449. [DOI] [PubMed] [Google Scholar]
  6. Ishino H., Okuma T., Motoike M. A case of nodular polioencephalitis with a history of 7 years. Folia Psychiatr Neurol Jpn. 1971;25(4):261–268. doi: 10.1111/j.1440-1819.1971.tb02916.x. [DOI] [PubMed] [Google Scholar]
  7. MOLLER F. Brain-stem encephalitis and epidemic vertigo. Acta Psychiatr Neurol Scand. 1956;31(1):107–115. [PubMed] [Google Scholar]
  8. MOLLER F., NENZELIUS C. Acute focal brain-stem lesions with favourable course. ("Brain stem encephalitis"). Acta Neurol Scand. 1961;37:297–316. doi: 10.1111/j.1600-0404.1961.tb01069.x. [DOI] [PubMed] [Google Scholar]
  9. Marsal J. Etude anatomo-clinique d'un cas d'encéphalite du tronc cérébral. Rev Neurol (Paris) 1967 Feb;116(2):141–160. [PubMed] [Google Scholar]
  10. Minauf M., Tateishi J. Sporadische "Hirnstammencephalitiden". Arch Psychiatr Nervenkr (1970) 1969;212(2):200–206. doi: 10.1007/BF00342980. [DOI] [PubMed] [Google Scholar]
  11. RUBINSTEIN L. J., URICH H. Meningo-encephalitis of Behcet's disease: case report with pathological findings. Brain. 1963 Mar;86:151–160. doi: 10.1093/brain/86.1.151. [DOI] [PubMed] [Google Scholar]
  12. Schain R. J., Wilson G. Brainstem encephalitis with radiographic evidence of medullary enlargement. Neurology. 1971 May;21(5):537–539. doi: 10.1212/wnl.21.5.537. [DOI] [PubMed] [Google Scholar]
  13. Shirabe T., Tatsuta E., Kuroiwa Y., Tanaka K. An autopsy case of brain stem encephalitis with spinal cord involvement. Folia Psychiatr Neurol Jpn. 1972;26(2):133–143. doi: 10.1111/j.1440-1819.1972.tb01118.x. [DOI] [PubMed] [Google Scholar]
  14. TATETSU S., INOUE T., TAKAKI M. [A CASE OF THE ENCEPHALITIS LOCALIZED MAINLY IN THE BRAIN STEM WITH THE DEMYELINATION OF THE UNILATERAL CENTRUM SEMIOVALE]. Seishin Shinkeigaku Zasshi. 1964 Feb;66:75–85. [PubMed] [Google Scholar]
  15. Tatetsu S., Toya G., Miyakawa T. [An autopsy case of brain stem-encephalitis]. Seishin Shinkeigaku Zasshi. 1968 Jan;70(1):1–10. [PubMed] [Google Scholar]
  16. Waxman S. G., Sabin T. D., Embree L. J. Subacute brain-stem encephalitis. J Neurol Neurosurg Psychiatry. 1974 Jul;37(7):811–816. doi: 10.1136/jnnp.37.7.811. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Yalaz K., Tinaztepe K. Brain stem encephalitis. Acta Paediatr Scand. 1974 Mar;63(2):235–240. doi: 10.1111/j.1651-2227.1974.tb04790.x. [DOI] [PubMed] [Google Scholar]

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