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. 1981 May;34(5):514–518. doi: 10.1136/jcp.34.5.514

A method for the quantification of human gastric G cell density in endoscopic biopsy specimens.

R L McIntyre, J Piris
PMCID: PMC493335  PMID: 7019255

Abstract

A previously described method for estimating G cell density in endoscopic biopsy specimens has been modified to take into account observations of the way in which specimens behave when they are deformed and some of the length-measuring characteristics of a grid used to measure the length of tissue profiles. The relationships between particle densities in sections and particle densities in tissue of which the sections are representative are discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Asnaes S., Johansen A. Variation in distribution of antral gastrin cells. Acta Pathol Microbiol Scand A. 1975 Nov;83(6):737–738. doi: 10.1111/j.1699-0463.1975.tb01405.x. [DOI] [PubMed] [Google Scholar]
  2. Creutzfeldt W., Arnold R., Creutzfeldt C., Track N. S. Mucosal gastrin concentration, molecular forms of gastrin, number and ultrastructure of G-cells in patients with duodenal ulcer. Gut. 1976 Oct;17(10):745–754. doi: 10.1136/gut.17.10.745. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Crivelli O., Pera A., Ferrari A., Rizzetto M., Lombardo L., Babando G., Verme G. G-cell counts in antral endoscopic biopsies by immunofluorescence. Scand J Gastroenterol. 1977;12(6):721–726. doi: 10.3109/00365527709181710. [DOI] [PubMed] [Google Scholar]
  4. Elias H., Hennig A., Schwartz D. E. Stereology: applications to biomedicalresearch. Physiol Rev. 1971 Jan;51(1):158–200. doi: 10.1152/physrev.1971.51.1.158. [DOI] [PubMed] [Google Scholar]
  5. Piris J., Whitehead R. An immunoperoxidase technique for the identification of gastrin-producing cells. J Clin Pathol. 1974 Oct;27(10):798–799. doi: 10.1136/jcp.27.10.798. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Piris J., Whitehead R. Gastin cells and fasting gastrin levels in duodenal ulcer patients: a quantitative study based on multiple biopsy specimens. J Clin Pathol. 1979 Feb;32(2):171–178. doi: 10.1136/jcp.32.2.171. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Stave R., Brandtzaeg P. Immunohistochemical investigation of gastrin-producing cells (G cells). Estimation of antral density, mucosal distribution, and total mass of G cells in resected stomachs from patients with peptic ulcer disease. Scand J Gastroenterol. 1978;13(2):199–203. doi: 10.3109/00365527809181748. [DOI] [PubMed] [Google Scholar]
  8. Weibel E. R. Stereological principles for morphometry in electron microscopic cytology. Int Rev Cytol. 1969;26:235–302. doi: 10.1016/s0074-7696(08)61637-x. [DOI] [PubMed] [Google Scholar]

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