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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1970 Aug;33(4):506–510. doi: 10.1136/jnnp.33.4.506

Fatty acid composition of phospholipids from platelets and erythrocytes in multiple sclerosis

S Gul 1,2, A D Smith 1,2, R H S Thompson 1,2, H Payling Wright 1,2, K J Zilkha 1,2
PMCID: PMC493509  PMID: 5505678

Abstract

The fatty acid composition of the phospholipids of red blood cells and blood platelets has been investigated in multiple sclerosis patients and in normal individuals. The variation in the platelet phospholipid fatty acid pattern in normals has been measured for the first time and has been shown to be small. The relative level of linoleate, expressed as a percentage of the five main fatty acids, was found to be significantly lower in the multiple sclerosis patients than in healthy individuals, both in the red cells and platelets. A highly significant correlation was found between serum linoleate and both platelet and red cell linoleate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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