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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1970 Dec;33(6):739–744. doi: 10.1136/jnnp.33.6.739

Limitations of circulation time in the diagnosis of intracranial disease1

J O Rowan 1,2,3, J N Cross 1,2,3, G M Tedeschi 1,2,3,2, W B Jennett 1,2,3
PMCID: PMC493586  PMID: 5531895

Abstract

The mode circulation time was measured using intravenously injected technetium 99m and a collimation system devised to discriminate between the right and left sides of the head. The results in 21 normal men were used as a basis of assessing the findings in 205 patients, made up of five diagnostic groups (ischaemia, haematoma, subarachnoid haemorrhage, intracranial tumour, and head injury). The average mode circulation time in the affected hemisphere for the three groups with vascular disease was increased, but even in these groups half the patients had a mode circulation time within 1 SD of normal mean; similar results were found for asymmetry between the hemispheres. In serial measurements in 45 patients no correlation was found between change in mode circulation time and the clinical state. That so many results are within the normal range limits the value of this method.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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