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. 1971 Apr;34(2):185–191. doi: 10.1136/jnnp.34.2.185

Motor neurone disease

Further evidence for an abnormality of nerve metabolism

Bhagwan Shahani 1,1, G A B Davies-Jones 1, W Ritchie Russell 1
PMCID: PMC493732  PMID: 4328410

Abstract

Physiological and biochemical studies were carried out on 16 patients with motor neurone disease (MND). It was confirmed that the peripheral nerves in cases of MND are often unusually resistant to ischaemia especially as regards the large sensory fibres. Biochemical investigations demonstrated a tendency to carbohydrate intolerance and abnormal pyruvate metabolism. When compared with other related studies in MND it seems very likely that there is a metabolic abnormality present in MND which demands further study.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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