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. 2016 Apr 12;71(7):594–600. doi: 10.1136/thoraxjnl-2015-208050

Figure 3.

Figure 3

Effect of exposing monocytes and monocyte-derived macrophages (MDMs) to Mycoplasma salivarium and lipopolysaccharide (LPS), on cytokine secretion. (A) TNF-α secretion by monocytes, p=0.0003 by ANOVA. (B) TNF-α secretion by MDMs, p=0.0024 by ANOVA. (C) Interleukin (IL) 6 secretion by monocytes, p=0.0006 by ANOVA. (D) IL-6 secretion by MDMs, p=0.04 by ANOVA. (E) IL-10 secretion by monocytes, p=0.02 by ANOVA. (F) IL-10 secretion by MDMs, p=0.004 by ANOVA. (G) IL-8 secretion by monocytes, p=0.55 by ANOVA. (H) IL-8 secretion by MDMs, p=0.0013 by ANOVA. *p<0.05, **p<0.01, ***p<0.001 by Bonferroni's post-hoc test, all other comparisons were non-significant by Bonferroni's test. Results are from duplicates of n=3 individual healthy donors, with 300 000 cells per well. Data shown as mean and SD. MOI, multiplicity of infection.