Table 1. Combination index (CI) of carfilzomib and CUDC-101 combinations.

Cell lines	Carf (nM)	CUDC (μM)	CIÙ
8505c	4.0	0.4	0.71
	6.0	0.8	0.51
	8.0	1.2	0.41
	10.0	1.6	0.48
	12.0	2.0	0.54
C-643	4.0	0.4	0.74
	6.0	0.8	0.48
	8.0	1.2	0.58
	10.0	1.6	0.80
	12.0	2.0	0.97
SW-1736	4.0	0.4	0.81
	6.0	0.8	0.79
	8.0	1.2	0.82
	10.0	1.6	0.86
	12.0	2.0	0.97
THJ-16T	6.0	0.4	0.85
	8.0	0.8	0.61
	10.0	1.2	0.66
	12.0	1.6	0.48
	14.0	2.0	0.68
THJ-29T	4.0	0.4	0.80
	6.0	0.8	0.82
	8.0	1.2	0.74
	10.0	1.6	0.59
	12.0	2.0	0.62

Ù The combination index (CI) was calculated according to the approach described by Chou and Talalay. CI = 1 indicates an additive effect, CI < 1 a synergistic effect, and CI > 1 an antagonistic effect.