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. 2016 Feb 24;7(13):16542–16566. doi: 10.18632/oncotarget.7665

Figure 13. PE4, PE5, PE6, PE8, PE12 and PE21 delay yeast chronological aging and have different effects on several longevity-defining cellular processes.

Figure 13

Arrows pointing at boxes with the terms of longevity-defining cellular processes denote activation of these processes, T bars denote inhibition of these processes, whereas lines with filled circles denote change in the age-related chronology of intracellular ROS. The thickness of such arrows, T bars and lines with filled circles correlates with the extent to which a PE activates, inhibits or alters the age-related chronology (respectively) of a particular longevity-defining cellular process. Arrows and T bars pointing at boxes with the term “AGING” denote acceleration or deceleration (respectively) of yeast chronological aging.