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. 2016 Feb 24;7(13):16542–16566. doi: 10.18632/oncotarget.7665

Figure 5. PE4, PE5, PE6, PE8, PE12 and PE21 alter the age-related chronology of mitochondrial oxygen consumption by yeast grown under non-CR conditions.

Figure 5

WT cells were grown in the synthetic minimal YNB medium initially containing 2% glucose, in the presence of a PE or in its absence. A polarographic assay was used to measure oxygen uptake by live yeast cells, as described in Materials and methods. Age-dependent changes in the rate of mitochondrial oxygen consumption by chronologically aging WT strain cultured under non-CR conditions on 2% glucose with or without 0.5% PE4 (A), 0.5% PE5 (B), 1% PE6 (C), 0.3% PE8 (D), 0.1% PE12 (E) or 0.1% PE21 (F) are shown; data are presented as means ± SEM (n = 7–9; *p < 0.05; the p values for comparing the means of two groups were calculated with the help of the GraphPad Prism statistics software using an unpaired two-tailed t test). Abbreviations: Logarithmic (L), post-diauxic (PD) or stationary (ST) growth phase.