Table 1. Characteristics of human head and neck squamous cell lines.
Cell lines | SQ20B | Cal33 | Cal27 | SCC61 |
---|---|---|---|---|
SF2 | 0.76 | 0.67 | 0.47 | 0.39 |
IC50 ABT-737 (μM) | 14.56 (± 1.67) | 9.48 (± 1.01) | 13.44 (± 1.37) | 2.38 (± 0.38) |
Protein expression (relative blot density to α-tubuline) (.10−7) | ||||
Bcl-2 | 1.11 | 4.28 | 1.89 | 3.94 |
Bcl-xL | 4.52 | 2.98 | 3.71 | 1.21 |
Mcl-1 | 4.70 | 7.66 | 5.85 | 2.09 |
Bax | 3.20 | 7.40 | 8.23 | 2.84 |
Bak | 1.44 | 1.53 | 2.15 | 2.51 |
PUMA | 0.70 | 0.89 | 0.40 | 0.98 |