Abstract
Nineteen patients with multiple sclerosis were treated with azathioprine for two years. There was no evidence that treatment prevented deterioration or reduced the number or severity of the relapses when compared with 24 control patients observed over the same period.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Cendrowski W. S. Multiple sclerosis: pilot therapeutic trial of immunosuppressants. Schweiz Arch Neurol Neurochir Psychiatr. 1969;105(2):241–246. [PubMed] [Google Scholar]
- Cendrowski W. S. Therapeutic trial of Imuran (azathioprine) in multiple sclerosis. Acta Neurol Scand. 1971;47(2):254–260. doi: 10.1111/j.1600-0404.1971.tb07480.x. [DOI] [PubMed] [Google Scholar]
- Corley C. C., Jr, Lessner H. E., Larsen W. E. Azathioprine therapy of "autoimmune" diseases. Am J Med. 1966 Sep;41(3):404–412. doi: 10.1016/0002-9343(66)90086-6. [DOI] [PubMed] [Google Scholar]
- Frick E., Angstwurm H., Späth G. Immunosuppressive Therapie der multiplen Sklerose. 1. Vorläufige Mitteilung der Behandlungsergebnisse mit Azathioprin und Antilymphozygenglobulin. Munch Med Wochenschr. 1971 Feb 12;113(7):221–231. [PubMed] [Google Scholar]
- KURTZKE J. F. On the evaluation of disability in multiple sclerosis. Neurology. 1961 Aug;11:686–694. doi: 10.1212/wnl.11.8.686. [DOI] [PubMed] [Google Scholar]
- Millar J. H., Vas C. J., Noronha M. J., Liversedge L. A., Rawson M. D. Long-term treatment of multiple sclerosis with corticotrophin. Lancet. 1967 Aug 26;2(7513):429–431. doi: 10.1016/s0140-6736(67)90850-1. [DOI] [PubMed] [Google Scholar]
- Tucker W. G., Kapphahn K. H. A preliminary evaluation of azathioprine (Imuran) in the treatment of multiple sclerosis. Henry Ford Hosp Med J. 1969 Summer;17(2):89–92. [PubMed] [Google Scholar]