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. 1973 Aug;36(4):625–629. doi: 10.1136/jnnp.36.4.625

Sites of origin in the central nervous system of monoamine metabolites measured in human cerebrospinal fluid1

E Garelis 1, T L Sourkes 1
PMCID: PMC494420  PMID: 4731331

Abstract

The concentrations of homovanillic acid (HVA) and 5-hydroxyindole-acetic acid (5-HIAA) were measured in five cases with partial or complete block of CSF circulation, at various levels. Determinations were made in both a lumbar and a cisternal, or `mixed', sample obtained during pneumoencephalography. Most of the HVA appears to enter the ventricular system at the lateral ventricles, whereas much of the 5-HIAA in CSF originates in lower neuronal structures, including the spinal cord. The spinal contribution to the 5-HIAA content of lumbar CSF is of the order of 23-37%.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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