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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1973 Oct;36(5):757–768. doi: 10.1136/jnnp.36.5.757

Brain abscess

Review of 89 cases over a period of 30 years

A J Beller 1, A Sahar 1, I Praiss 1
PMCID: PMC494454  PMID: 4585071

Abstract

Eighty-nine cases of brain abscess, diagnosed over a period of 30 years, are reviewed. The incidence of this disease did not decline throughout the period. Abscesses of ear and nose origin constituted the largest group (38%). Postoperative abscesses seem to have increased in incidence, presumably due to routine postoperative antibiotic treatment. Antibiotics were possibly responsible for the suppression of signs of infection in 45% of the patients, who presented as suffering from a space-occupying lesion. The most accurate diagnostic tool was angiography, which localized the lesion in 90% and suggested its nature in 61%. Brain scan may prove as satisfactory. Staphylococcus was cultured in about two-thirds of the cases. Mortality seemed to decrease concomitantly with the advent of more potent antibiotics. The treatment of choice in terms of both mortality and morbidity seemed to be enucleation after previous sterilization. The hazards of radical surgery should be taken into consideration.

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Selected References

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  1. BALLANTINE H. T., Jr, SHEALY C. N. The role of radical surgery in the treatment of abscess of the brain. Surg Gynecol Obstet. 1959 Sep;109:370–374. [PubMed] [Google Scholar]
  2. BELLER A. J. The syndrome of brain abscess with congenital cardiac disease; report on a case with complete recovery. J Neurosurg. 1951 Mar;8(2):239–243. doi: 10.3171/jns.1951.8.2.0239. [DOI] [PubMed] [Google Scholar]
  3. Garfield J. Management of supratentorial intracranial abscess: a review of 200 cases. Br Med J. 1969 Apr 5;2(5648):7–11. doi: 10.1136/bmj.2.5648.7. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Gregory D. H., Messner R., Zinneman H. H. Metastatic brain abscesses. A retrospective appraisal of 29 patients. Arch Intern Med. 1967 Jan;119(1):25–31. doi: 10.1001/archinte.119.1.25. [DOI] [PubMed] [Google Scholar]
  5. JOOMA O. V., PENNYBACKER J. B., TUTTON G. K. Brain abscess: aspiration, drainage, or excision? J Neurol Neurosurg Psychiatry. 1951 Nov;14(4):308–313. doi: 10.1136/jnnp.14.4.308. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. KERR F. W., KING R. B., MEAGHER J. N. Brain abscess: a study of forty-seven consecutive cases. J Am Med Assoc. 1958 Oct 18;168(7):868–872. doi: 10.1001/jama.1958.03000070024005. [DOI] [PubMed] [Google Scholar]
  7. KING J. E., TURNEY F. Brain abscess; evolution of the methods of treatment. Ann Surg. 1954 May;139(5):587–612. doi: 10.1097/00000658-195405000-00006. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. LEWIN W. Recent developments in the management of brain abscess. Br Med J. 1955 Mar 12;1(4914):631–634. doi: 10.1136/bmj.1.4914.631. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. LISKE E., WEIKERS N. J. CHANGING ASPECTS OF BRAIN ABSCESSES. REVIEW OF CASES IN WISCONSIN 1940 THROUGH 1962. Neurology. 1964 Apr;14:294–300. doi: 10.1212/wnl.14.4.294. [DOI] [PubMed] [Google Scholar]
  10. PENNYBACKER J., DIXON J. W., FULTON CHRISTIE J., DAWES J. D. Discussion on intracranial complications of otogenic origin. Proc R Soc Med. 1961 Apr;54:309–320. doi: 10.1177/003591576105400415. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. SALIBI B. BACTEROIDES INFECTION OF THE BRAIN. SUCCESSFUL MANAGEMENT OF CASE WITH THREE INTRACRANIAL ABSCESSES. Arch Neurol. 1964 Jun;10:629–634. doi: 10.1001/archneur.1964.00460180095009. [DOI] [PubMed] [Google Scholar]
  12. SPERL M. P., Jr, MACCARTY C. S., WELLMAN W. E. Observations on current therapy of abscess of the brain. AMA Arch Neurol Psychiatry. 1959 Apr;81(4):439–441. doi: 10.1001/archneurpsyc.1959.02340160037006. [DOI] [PubMed] [Google Scholar]
  13. TUTTON G. K. Cerebral abscess--the present position. Ann R Coll Surg Engl. 1953 Nov;13(5):281–311. [PMC free article] [PubMed] [Google Scholar]
  14. Tefft M., Matson D. D., Neuhauser E. B. Brain abscess in children. Radiologic methods for early recognition. Am J Roentgenol Radium Ther Nucl Med. 1966 Nov;98(3):675–688. [PubMed] [Google Scholar]

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