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. 1974 Jan;37(1):21–26. doi: 10.1136/jnnp.37.1.21

Periaqueductal dysfunction (the Sylvian aqueduct syndrome): a sign of hydrocephalus?

Michael Swash 1
PMCID: PMC494558  PMID: 4544322

Abstract

A patient with hydrocephalus due to aqueductal occlusion is described in whom the Sylvian aqueduct syndrome appeared during a sudden increase in intracranial pressure. The ocular signs resolved completely when the hydrocephalus was relieved. Marked dilatation of the posterior part of the third ventricle and of the rostral aqueduct with axial displacement of these structures was demonstrated radiologically. It is suggested that the ocular signs in this case were the result of periaqueductal dysfunction due to assimilation and dilatation of the aqueduct, with secondary tentorial block. This abnormality may be the cause of the similar abnormalities commonly found in noncommunicating hydrocephalus in both infants and adults.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ASKENASY H., WIJSENBEEK H., HERZBERGER E. Retraction nystagmus and retraction of eyelids due to arteriovenous aneurysm of midbrain. AMA Arch Neurol Psychiatry. 1953 Feb;69(2):236–241. doi: 10.1001/archneurpsyc.1953.02320260094007. [DOI] [PubMed] [Google Scholar]
  2. BECKETT R. S., NETSKY M. G., ZIMMERMAN H. M. Developmental stenosis of the aqueduct of Sylvius. Am J Pathol. 1950 Sep;26(5):755–787. [PMC free article] [PubMed] [Google Scholar]
  3. CHRISTOFF N., ANDERSON P. J., BENDER M. B. Convergence and retractory nystagmus. Trans Am Neurol Assoc. 1960;85:29–32. [PubMed] [Google Scholar]
  4. FOLTZ E. L., WARD A. A., Jr Communicating hydrocephalus from subarachnoid bleeding. J Neurosurg. 1956 Nov;13(6):546–566. doi: 10.3171/jns.1956.13.6.0546. [DOI] [PubMed] [Google Scholar]
  5. Fredericks E. J., Van Nuis C. Diverticulum of the rostral cerebral aqueduct with ocular dysfunctions. Arch Neurol. 1967 Jan;16(1):32–36. doi: 10.1001/archneur.1967.00470190036004. [DOI] [PubMed] [Google Scholar]
  6. Hakim S., Adams R. D. The special clinical problem of symptomatic hydrocephalus with normal cerebrospinal fluid pressure. Observations on cerebrospinal fluid hydrodynamics. J Neurol Sci. 1965 Jul-Aug;2(4):307–327. doi: 10.1016/0022-510x(65)90016-x. [DOI] [PubMed] [Google Scholar]
  7. Hatcher M. A., Jr, Klintworth G. K. The sylvian aqueduct syndrome. A clinicopathologic study. Arch Neurol. 1966 Aug;15(2):215–222. doi: 10.1001/archneur.1966.00470140105015. [DOI] [PubMed] [Google Scholar]
  8. Hill M. E., Lougheed W. M., Barnett H. J. A treatable form of dementia due to normal-pressure, communicating hydrocephalus. Can Med Assoc J. 1967 Nov 25;97(22):1309–1320. [PMC free article] [PubMed] [Google Scholar]
  9. Jakubowski J., Jefferson A. Axial enlargement of the 3rd ventricle, and displacement of the brain-stem in benign aqueduct stenosis. J Neurol Neurosurg Psychiatry. 1972 Feb;35(1):114–123. doi: 10.1136/jnnp.35.1.114. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. MCHUGH P. R. OCCULT HYDROCEPHALUS. Q J Med. 1964 Apr;33:297–308. [PubMed] [Google Scholar]
  11. Messert B., Baker N. H. Syndrome of progressive spastic ataxia and apraxia associated with occult hydrocephalus. Neurology. 1966 May;16(5):440–452. doi: 10.1212/wnl.16.5.440. [DOI] [PubMed] [Google Scholar]
  12. NATHANSON M., EPSTEIN J. A. Convergence nystagmus and paralysis of vertical gaze following balloon-made lesion for parkinsonism. Sequence of events during recovery. Trans Am Neurol Assoc. 1962;87:227–228. [PubMed] [Google Scholar]
  13. Nag T. K., Falconer M. A. Non-tumoral stenosis of the aqueduct in adults. Br Med J. 1966 Nov 12;2(5523):1168–1170. doi: 10.1136/bmj.2.5523.1168. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. PETIT-DUTAILLIS D., THIEBAUT F., BERDET H., BARBIZET J. A propos des sténoses de l'aqueduc de Sylvius d'origine non tumorale de l'adolescent et de l'adulte. Rev Neurol (Paris) 1950 May;82(5):417–421. [PubMed] [Google Scholar]
  15. Pennybacker J. Stenosis of the Aqueduct of Sylvius: (Section of Neurology). Proc R Soc Med. 1940 Jun;33(8):507–512. [PMC free article] [PubMed] [Google Scholar]
  16. SEGARRA J. M., OJEMAN R. J. Convergence nystagmus. Neurology. 1961 Oct;11:883–893. doi: 10.1212/wnl.11.10.883. [DOI] [PubMed] [Google Scholar]
  17. SMITH J. L., ZIEPER I., GAY A. J., COGAN D. G. Nystagmus retractorius. Arch Ophthalmol. 1959 Nov;62:864–867. doi: 10.1001/archopht.1959.04220050124020. [DOI] [PubMed] [Google Scholar]

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