Abstract
An acromegalic man aged 70 developed progressive polyneuropathy affecting mainly the extremities. The peripheral nerves showed hypertrophic neuropathy and accumulation of acid mucopolysaccharides in the nerve without `onion bulb' formation. The myelin showed a lamellar disintegration and vesicular formation. It is suggested that the association of these findings represents a pathological entity, acromegalic polyneuropathy.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Buchthal F., Rosenfalck A. Sensory potentials in polyneuropathy. Brain. 1971;94(2):241–262. doi: 10.1093/brain/94.2.241. [DOI] [PubMed] [Google Scholar]
- Catt K. J. Growth hormone. Lancet. 1970 May 2;1(7653):933–939. doi: 10.1016/s0140-6736(70)91059-7. [DOI] [PubMed] [Google Scholar]
- Fardeau M., Abelanet R., Laudat P., Bonduelle M. Maladie de refsum. Etude histologique, ultrastructurale et biochimique d'une biopsie de nerf périphérique. Addendum au mémoire de 1966. Rev Neurol (Paris) 1970 Mar;122(3):185–196. [PubMed] [Google Scholar]
- Flament-Durand J., Noel P., Rutsaert J., Toussaint D., Malmendier C., Lyon G. A case of Refsum's disease: clinical, pathological, ultrastructural and biochemical study. Pathol Eur. 1971;6(2):172–191. [PubMed] [Google Scholar]
- Lampert P. W., Garrett R. S. Mechanism of demyelination in tellurium neuropathy. Electron microscopic observations. Lab Invest. 1971 Nov;25(5):380–388. [PubMed] [Google Scholar]
- Lampert P. W. Mechanism of demyelination in experimental allergic neuritis. Electron microscopic studies. Lab Invest. 1969 Feb;20(2):127–138. [PubMed] [Google Scholar]
- Lampert P. W., Schochet S. S., Jr Demyelination and remyelination in lead neuropathy. Electron microscopic studies. J Neuropathol Exp Neurol. 1968 Oct;27(4):527–545. [PubMed] [Google Scholar]
- Lampert P. Electron microscopic studies on ordinary and hyperacute experimental allergic encephalomyelitis. Acta Neuropathol. 1967 Oct 20;9(2):99–126. doi: 10.1007/BF00691436. [DOI] [PubMed] [Google Scholar]
- Lampert P., Garro F., Pentschew A. Tellurium neuropathy. Acta Neuropathol. 1970;15(4):308–317. doi: 10.1007/BF00684729. [DOI] [PubMed] [Google Scholar]
- Lewis P. D. Neuromuscular involvement in pituitary gigantism. Br Med J. 1972 May 27;2(5812):499–500. doi: 10.1136/bmj.2.5812.499. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lucey C. Neuromuscular involvement in pituitary gigantism. Br Med J. 1972 Jul 1;3(5817):49–50. doi: 10.1136/bmj.3.5817.49-c. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Masurovsky E. B., Bunge M. B., Bunge R. P. Cytological studies of organotypic cultures of rat dorsal root ganglia following X-irradiation in vitro. II. Changes in Schwann cells, myelin sheaths, and nerve fibers. J Cell Biol. 1967 Feb;32(2):497–518. doi: 10.1083/jcb.32.2.497. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Thomas P. K., Lascelles R. G. Hypertrophic neuropathy. Q J Med. 1967 Apr;36(142):223–238. [PubMed] [Google Scholar]
- Wiśniewski H., Prineas J., Raine C. S. An ultrastructural study of experimental demyelination and remyelination. I. Acute experimental allergic encephalomyelitis in the peripheral nervous system. Lab Invest. 1969 Aug;21(2):105–118. [PubMed] [Google Scholar]
- Wiśniewski H., Raine C. S. An ultrastructural study of experimental demyelination and remyelination. V. Central and peripheral nervous system lesions caused by diphtheria toxin. Lab Invest. 1971 Jul;25(1):73–80. [PubMed] [Google Scholar]