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. 1974 Oct;37(10):1166–1176. doi: 10.1136/jnnp.37.10.1166

Encephalitis associated with carcinoma

Central hypoventilation syndrome and cytoplasmic inclusion bodies

Allen M Kaplan 1,2,3, Hideo H Itabashi 1,2,3,1
PMCID: PMC494863  PMID: 4374509

Abstract

A case of encephalitis associated with a remote and occult oat cell carcinoma is presented in which the main clinical features were progressive dementia and central hypoventilation syndrome. The only significant anatomical lesions within the known anatomical substrate of respiration affected the locus caeruleus on both sides. It is speculated that the degeneration of the locus caeruleus was responsible for the central hypoventilation syndrome. Hitherto undescribed neuronal intracytoplasmic eosinophilic inclusions were found in an isolated lesion of the insular cortex. Electron microscopy failed to disclose viral particles in the regions of neuronal degeneration.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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