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. 1991 Dec;44(12):1034–1036. doi: 10.1136/jcp.44.12.1034

Pulmonary infarction, myocardial infarction, and acute disseminated intravascular coagulation.

F J Thomson 1, E W Benbow 1, R F McMahon 1, C M Cheshire 1
PMCID: PMC494978  PMID: 1791208

Abstract

Pulmonary and myocardial damage are frequently cited as manifestations of disseminated intravascular coagulation (DIC), but rarely as causes. Three elderly cases of severe DIC due to pulmonary and myocardial infarction are reported. All three patients died. Necropsy showed extensive pulmonary emboli in each case with large pulmonary infarcts in cases 1 and 2 and a ventricular aneurysm containing thrombus in cases 2 and 3. Early diagnosis and treatment of pulmonary embolism requires a high degree of clinical suspicion but may prevent progression to the irreversible stage of severe DIC.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Astrup T. Assay and content of tissue thromboplastin in different organs. Thromb Diath Haemorrh. 1965 Nov 15;14(3-4):401–416. [PubMed] [Google Scholar]
  2. Cade J., Hirsh J., Regoeczi E. Mechanisms for elevated fibrin/fibrinogen degradation products in acute experimental pulmonary embolism. Blood. 1975 Apr;45(4):563–568. [PubMed] [Google Scholar]
  3. Caracci B. F., Rumbolo P. M., Mainini S., Walker H. S., 3rd, Peterson G. J. How accurate are ventilation-perfusion scans for pulmonary embolism? Am J Surg. 1988 Dec;156(6):477–480. doi: 10.1016/s0002-9610(88)80533-6. [DOI] [PubMed] [Google Scholar]
  4. Caracci B. F., Rumbolo P. M., Mainini S., Walker H. S., 3rd, Peterson G. J. How accurate are ventilation-perfusion scans for pulmonary embolism? Am J Surg. 1988 Dec;156(6):477–480. doi: 10.1016/s0002-9610(88)80533-6. [DOI] [PubMed] [Google Scholar]
  5. Mant M. J., King E. G. Severe, acute disseminated intravascular coagulation. A reappraisal of its pathophysiology, clinical significance and therapy based on 47 patients. Am J Med. 1979 Oct;67(4):557–563. doi: 10.1016/0002-9343(79)90225-0. [DOI] [PubMed] [Google Scholar]
  6. McKay D. G., Franciosi R., Zeller J. Symposium on thrombohemorrhagic phenomena. II. Am J Cardiol. 1967 Sep;20(3):374–380. doi: 10.1016/0002-9149(67)90061-6. [DOI] [PubMed] [Google Scholar]
  7. Okuno T., Nelson C. Value of determination of serum fibrin-fibrinogen degradation products in acute myocardial infarction. Am J Clin Pathol. 1974 Feb;61(2):155–159. doi: 10.1093/ajcp/61.2.155. [DOI] [PubMed] [Google Scholar]
  8. Preston F. E. Disseminated intravascular coagulation. Br J Hosp Med. 1982 Aug;28(2):129–137. [PubMed] [Google Scholar]
  9. Ruckley C. V., Das P. C., Leitch A. G., Donaldson A. A., Copland W. A., Redpath A. T., Scott P., Cash J. D. Serum fibrin-fibrinogen degradation products associated with postoperative pulmonary embolus and venous thrombosis. Br Med J. 1970 Nov 14;4(5732):395–398. doi: 10.1136/bmj.4.5732.395. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Sculier J. P., Coune A., Vandenbossche J. L., Muller C. Intracardiac thrombosis associated with an acute consumption coagulopathy. Cardiology. 1987;74(1):58–61. doi: 10.1159/000174176. [DOI] [PubMed] [Google Scholar]
  11. Stahl R. L., Javid J. P., Lackner H. Unrecognized pulmonary embolism presenting as disseminated intravascular coagulation. Am J Med. 1984 May;76(5):772–778. doi: 10.1016/0002-9343(84)90985-9. [DOI] [PubMed] [Google Scholar]

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