Abstract
A 30 year old woman with recurrent anaemia due to folate deficiency had evidence of sarcoid granuloma on small bowel biopsy but was presumed to have Crohn's disease. The diagnosis of small bowel sarcoidosis was not seriously considered until she developed systemic manifestations of sarcoidosis (cutaneous and pulmonary lesions) over the following 20 years. Sarcoidosis of the gastrointestinal tract, particularly the small bowel, is rare and this case is unusual because bowel pathology preceded more generalised lesions. As far as is known it is also the first case to be described presenting with malabsorption of folic acid.
Full text
PDFImages in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bulger K., O'Riordan M., Purdy S., O'Brien M., Lennon J. Gastrointestinal sarcoidosis resembling Crohn's disease. Am J Gastroenterol. 1988 Dec;83(12):1415–1417. [PubMed] [Google Scholar]
- Clague R. B. Sarcoidosis or Crohn's disease? Br Med J. 1972 Sep 30;3(5830):804–804. doi: 10.1136/bmj.3.5830.804. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lemann M., Messing B., D'Agay F., Modigliani R. Crohn's disease with respiratory tract involvement. Gut. 1987 Dec;28(12):1669–1672. doi: 10.1136/gut.28.12.1669. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Miyamoto C., Nomura S., Kudo E., Hamamoto Y. An autopsy case of sarcoidosis of the intestinal canal. Bull Osaka Med Sch. 1972 Jun;18(1):48–55. [PubMed] [Google Scholar]
- Rauf A., Davis P., Levendoglu H. Sarcoidosis of the small intestine. Am J Gastroenterol. 1988 Feb;83(2):187–189. [PubMed] [Google Scholar]
- Siltzbach L. E., Vieira L. O., Topilsky M., Janowitz H. D. Is there Kveim responsiveness in Crohn's disease? Lancet. 1971 Sep 18;2(7725):634–636. doi: 10.1016/s0140-6736(71)80072-7. [DOI] [PubMed] [Google Scholar]
- Sprague R., Harper P., McClain S., Trainer T., Beeken W. Disseminated gastrointestinal sarcoidosis. Case report and review of the literature. Gastroenterology. 1984 Aug;87(2):421–425. [PubMed] [Google Scholar]
- Tinker M. A., Viswanathan B., Laufer H., Margolis I. B. Acute appendicitis and pernicious anemia as complications of gastrointestinal sarcoidosis. Am J Gastroenterol. 1984 Nov;79(11):868–872. [PubMed] [Google Scholar]
- Tweedie J. H., McCann B. G. Metastatic Crohn's disease of thigh and forearm. Gut. 1984 Feb;25(2):213–214. doi: 10.1136/gut.25.2.213. [DOI] [PMC free article] [PubMed] [Google Scholar]