Abstract
Results obtained with a recently introduced enzyme immunoassay system (EIA) for the detection of cryptococcal antigen (Meridian Diagnostics Inc) were compared with those obtained by a latex agglutination (LA) method (Immuno-Mycologics, Norman, Oklahoma, USA). Fifty four samples were examined. There was 92% agreement between the two methods. One false positive result was obtained with LA, and one sample was inevaluable. The EIA was rapid and simple to perform. There was some evidence that it gave fewer false positive reactions and improved the diagnosis of genuine early cases.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Gade W., Hinnefeld S. W., Babcock L. S., Gilligan P., Kelly W., Wait K., Greer D., Pinilla M., Kaplan R. L. Comparison of the PREMIER cryptococcal antigen enzyme immunoassay and the latex agglutination assay for detection of cryptococcal antigens. J Clin Microbiol. 1991 Aug;29(8):1616–1619. doi: 10.1128/jcm.29.8.1616-1619.1991. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Patterson T. F., Andriole V. T. Current concepts in cryptococcosis. Eur J Clin Microbiol Infect Dis. 1989 May;8(5):457–465. doi: 10.1007/BF01964060. [DOI] [PubMed] [Google Scholar]