Abstract
A post mortem examination of a 70 year old man, who died three years after a poorly differentiated adenocarcinoma of prostate had been diagnosed, showed widespread signet-ring cell carcinoma, with an associated linitis plastica. The signet-ring cells stained positively with prostatic specific antigen and with prostatic specific acid phosphatase, but failed to react with mucopolysaccharide staining. The electron microscopic appearance of the signet-ring cell tumour was due to the presence of large cytoplasmic vacuoles. This case emphasises the possibility that cases of metastatic signet-ring cell carcinoma may be prostatic in origin. This can be confirmed by specific immunohistochemical studies.
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- Cormier W. J., Gaffey T. A., Welch J. M., Welch J. S., Edmonson J. H. Linitis plastica caused by metastatic lobular carcinoma of the breast. Mayo Clin Proc. 1980 Dec;55(12):747–753. [PubMed] [Google Scholar]
- Cricco R. P., Kassis J. Mucinous adenocarcinoma of prostate. Urology. 1979 Sep;14(3):276–278. doi: 10.1016/0090-4295(79)90501-6. [DOI] [PubMed] [Google Scholar]
- Epstein J. I., Lieberman P. H. Mucinous adenocarcinoma of the prostate gland. Am J Surg Pathol. 1985 Apr;9(4):299–308. doi: 10.1097/00000478-198504000-00006. [DOI] [PubMed] [Google Scholar]
- Giltman L. I. Signet ring adenocarcinoma of the prostate. J Urol. 1981 Jul;126(1):134–135. doi: 10.1016/s0022-5347(17)54414-6. [DOI] [PubMed] [Google Scholar]
- Lipski P. S., Bennett M. K., Kelly P. J., James O. F. Ageing and duodenal morphometry. J Clin Pathol. 1992 May;45(5):450–452. doi: 10.1136/jcp.45.5.450. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Odom D. G., Donatucci C. F., Deshon G. E. Mucinous adenocarcinoma of the prostate. Hum Pathol. 1986 Aug;17(8):863–865. doi: 10.1016/s0046-8177(86)80210-6. [DOI] [PubMed] [Google Scholar]
- Tannenbaum M. Mucin-secreting carcinoma of prostate. Urology. 1975 Apr;5(4):543–544. doi: 10.1016/0090-4295(75)90088-6. [DOI] [PubMed] [Google Scholar]