Abstract
AIMS: To determine which factors influence a clinician's decision to request a necropsy. METHODS: Patient age, confidence in premortem diagnosis, relatives' attitudes, and conditions of necropsy practice were combined factorially (two levels each) in separate medical and surgical questionnaires based on clinical case histories. The interactions between the factors were measured by a repeated measures factorial analysis of variance for each of the two clinical groups. The influence of the clinician's interest in necropsies on these interactions was also examined by a similar method. RESULTS: Necropsies were more likely to be requested on young patients, when diagnostic confidence was low, and when relatives' attitudes were favourable. Conditions of necropsy practice did not affect the likelihood of a request and there was no apparent overall difference in necropsy requests between the two groups of clinicians. The "patient age" and "relatives" factors had less influence on the decision of the surgical group to request necropsy. This was attributed to the opportunity to "see for themselves" at operation and was supported by the finding that surgeons were very likely to request necropsies in the absence of surgical intervention. Clinicians from both groups with a high pre-existing interest in the necropsy were consistently more likely to request necropsies. CONCLUSIONS: The "case history" based questionnaires successfully measured the relative influence of multiple factors in relation to the decision of clinicians to request a necropsy. These findings suggest that any attempt to reverse the decline in necropsy rates should focus on changing the clinician's perception of the value of the modern necropsy.
Full text
PDF



Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- ANDERSEN M. N. THE PROBLEM OF AUTOPSY CONSENT IN A TEACHING HOSPITAL. J Med Educ. 1964 May;39:518–521. [PubMed] [Google Scholar]
- Anderson N. H., Shanks J. H., McCluggage G. W., Toner P. G. Necropsies in clinical audit. J Clin Pathol. 1989 Sep;42(9):897–901. doi: 10.1136/jcp.42.9.897. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Anderson R. E., Hill R. B., Gorstein F. A model for the autopsy-based quality assessment of medical diagnostics. Hum Pathol. 1990 Feb;21(2):174–181. doi: 10.1016/0046-8177(90)90126-p. [DOI] [PubMed] [Google Scholar]
- Anderson R. E., Hill R. B., Key C. R. The sensitivity and specificity of clinical diagnostics during five decades. Toward an understanding of necessary fallibility. JAMA. 1989 Mar 17;261(11):1610–1617. [PubMed] [Google Scholar]
- Anderson R. E., Hill R. B. The current status of the autopsy in academic medical centers in the United States. Am J Clin Pathol. 1989 Oct;92(4 Suppl 1):S31–S37. [PubMed] [Google Scholar]
- Brown H. G. Lay perceptions of autopsy. Arch Pathol Lab Med. 1984 Jun;108(6):446–448. [PubMed] [Google Scholar]
- Brown H. G. Perceptions of the autopsy: views from the lay public and program proposals. Hum Pathol. 1990 Feb;21(2):154–158. doi: 10.1016/0046-8177(90)90123-m. [DOI] [PubMed] [Google Scholar]
- Cameron H. M., McGoogan E. A prospective study of 1152 hospital autopsies: II. Analysis of inaccuracies in clinical diagnoses and their significance. J Pathol. 1981 Apr;133(4):285–300. doi: 10.1002/path.1711330403. [DOI] [PubMed] [Google Scholar]
- Cameron H. M., McGoogan E., Watson H. Necropsy: a yardstick for clinical diagnoses. Br Med J. 1980 Oct 11;281(6246):985–988. doi: 10.1136/bmj.281.6246.985. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Chana J., Rhys-Maitland R., Hon P., Scott P., Thomas C., Hopkins A. Who asks permission for an autopsy? J R Coll Physicians Lond. 1990 Jul;24(3):185–188. [PMC free article] [PubMed] [Google Scholar]
- Cottreau C., McIntyre L., Favara B. E. Professional attitudes toward the autopsy. A survey of clinicians and pathologists. Am J Clin Pathol. 1989 Nov;92(5):673–676. doi: 10.1093/ajcp/92.5.673. [DOI] [PubMed] [Google Scholar]
- Friederici H. H. Reflections on the postmortem audit. JAMA. 1988 Dec 16;260(23):3461–3465. [PubMed] [Google Scholar]
- Goldman L., Sayson R., Robbins S., Cohn L. H., Bettmann M., Weisberg M. The value of the autopsy in three medical eras. N Engl J Med. 1983 Apr 28;308(17):1000–1005. doi: 10.1056/NEJM198304283081704. [DOI] [PubMed] [Google Scholar]
- Harrison M., Hourihane D. O. Quality assurance programme for necropsies. J Clin Pathol. 1989 Nov;42(11):1190–1193. doi: 10.1136/jcp.42.11.1190. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Karwinski B., Hartveit F. Death certification: increased clinical confidence in diagnosis and lack of interest in confirmation by necropsy is not justified. J Clin Pathol. 1989 Jan;42(1):13–17. doi: 10.1136/jcp.42.1.13. [DOI] [PMC free article] [PubMed] [Google Scholar]
- King D. W. Potential of the autopsy. Arch Pathol Lab Med. 1984 Jun;108(6):439–443. [PubMed] [Google Scholar]
- McGoogan E., Cameron H. M. Clinical attitudes to the autopsy. Scott Med J. 1978 Jan;23(1):19–22. doi: 10.1177/003693307802300106. [DOI] [PubMed] [Google Scholar]
- McGoogan E. The autopsy and clinical diagnosis. J R Coll Physicians Lond. 1984 Oct;18(4):240–243. [PMC free article] [PubMed] [Google Scholar]
- McPhee S. J., Bottles K. Autopsy: moribund art or vital science? Am J Med. 1985 Jan;78(1):107–113. doi: 10.1016/0002-9343(85)90470-x. [DOI] [PubMed] [Google Scholar]
- McPhee S. J., Bottles K., Lo B., Saika G., Crommie D. To redeem them from death. Reactions of family members to autopsy. Am J Med. 1986 Apr;80(4):665–671. doi: 10.1016/0002-9343(86)90822-3. [DOI] [PubMed] [Google Scholar]
- Mercer J., Talbot I. C. Clinical diagnosis: a post-mortem assessment of accuracy in the 1980s. Postgrad Med J. 1985 Aug;61(718):713–716. doi: 10.1136/pgmj.61.718.713. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Peacock S. J., Machin D., Duboulay C. E., Kirkham N. The autopsy: a useful tool or an old relic? J Pathol. 1988 Sep;156(1):9–14. doi: 10.1002/path.1711560105. [DOI] [PubMed] [Google Scholar]
- Puxty J. A., Horan M. A., Fox R. A. Necropsies in the elderly. Lancet. 1983 Jun 4;1(8336):1262–1264. doi: 10.1016/s0140-6736(83)92708-3. [DOI] [PubMed] [Google Scholar]
- Roberts W. C. The autopsy: its decline and a suggestion for its revival. N Engl J Med. 1978 Aug 17;299(7):332–338. doi: 10.1056/NEJM197808172990704. [DOI] [PubMed] [Google Scholar]
- Schned A. R., Mogielnicki R. P., Stauffer M. E. A comprehensive quality assessment program on the autopsy service. Am J Clin Pathol. 1986 Aug;86(2):133–138. doi: 10.1093/ajcp/86.2.133. [DOI] [PubMed] [Google Scholar]
- Silvestri F., Bussani R., Giarelli L. High autopsy rate in Trieste, 1901-1985: age associated increase in necroscopy practice. Pathologica. 1988 Sep-Oct;80(1069):523–532. [PubMed] [Google Scholar]
- Svendsen E., Hill R. B. Autopsy legislation and practice in various countries. Arch Pathol Lab Med. 1987 Sep;111(9):846–850. [PubMed] [Google Scholar]
- Underwood J. C., Cotton D. W., Stephenson T. J. Audit and necropsy. Lancet. 1989 Feb 25;1(8635):442–442. doi: 10.1016/s0140-6736(89)90039-1. [DOI] [PubMed] [Google Scholar]
- Waldron H. A., Vickerstaff L. Necropsy rates in the United Birmingham Hospitals. Br Med J. 1975 May 10;2(5966):326–328. doi: 10.1136/bmj.2.5966.326. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Webster J. R., Jr, Derman D., Kopin J., Glassroth J., Patterson R. Obtaining permission for an autopsy: its importance for patients and physicians. Am J Med. 1989 Mar;86(3):325–326. doi: 10.1016/0002-9343(89)90305-7. [DOI] [PubMed] [Google Scholar]