Effects of NT-3 with 20nM on mitogen-activated protein kinase (MAPK) activation in HNC at 0, 2, 4, 8 and 12 h. a The expression of ERK1/2, JNKs, p38 and phosphorylated ERK1/2, phosphorylated JNKs, and phosphorylated p38. b Contrast gray value of phosphorylated ERK1/2, phosphorylated JNKs, and phosphorylated p38. *There was significantly difference between two groups (P < 0.05)