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. 1992 Aug 1;89(15):6856–6860. doi: 10.1073/pnas.89.15.6856

pokkuri, a Drosophila gene encoding an E-26-specific (Ets) domain protein, prevents overproduction of the R7 photoreceptor.

H Tei 1, I Nihonmatsu 1, T Yokokura 1, R Ueda 1, Y Sano 1, T Okuda 1, K Sato 1, K Hirata 1, S C Fujita 1, D Yamamoto 1
PMCID: PMC49603  PMID: 1495974

Abstract

Studies on sevenless and bride of sevenless genes have revealed that the R8 cell plays a key role in the fate of the R7 photoreceptor cell, presenting on its surface an inductive cue to which R7 responds. sev-independent induction of R7 cells has been reported in the seven-up mutation, which appears to transform R1 and R6 cells to R7 cells. We have induced recessive mutations in a gene pokkuri (pok; pokkuri is a Japanese word that means "dropping dead") that lead to overproduction of R7 cells with rather minor effects on outer photoreceptors and R8 cells. Pok protein may function as a transcription factor, as the predicted amino acid sequence contains a region similar to the consensus established for the E-26-specific (Ets) domain.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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