Article Title: Improving target cell specificity using a novel monovalent bispecific IgG design
Authors(s): Yariv Mazor, Vaheh Oganesyan, Chunning Yang, Anna Hansen, Jihong Wang, Hongji Liu, Kris Sachsenmeier, Marcia Carlson, Dhanesh V. Gadre, Martin Jack Borrok, Xiang-Qing Yu, William Dall'Acqua, Herren Wu, and Partha Sarathi Chowdhury
Journal: mAbs
Bibliometrics: Published in Volume 7, Issue 2, pp. 377–389
DOI: 10.1080//19420862.2015.1007816
Publisher: Taylor & Francis
Following re-examination of the raw data used for the generation of Figure 7B in the paper “Improving target cell specificity using a novel monovalent bispecific IgG design” by Mazor et al., published in mAbs 7.2, pages 377–389 (DOI: 10.1080//19420862.2015.1007816), the authors identified an error in the X-axis antibody concentrations we had initially reported. The error was the consequence of mistakenly grafting the cytotoxicity values into a template Prism file already containing X-axis antibody concentrations starting at 66.67 µg//ml, while the correct antibody concentrations used for the specific experiment had started at a lower concentration of 1.875 µg//ml. The correct Figure 7B is shown here.
Figure 7.
Biological activities of EGFR-HER2 DuetMab. (B) ADCC assay with SK-OV3 cells. Each point represents the mean values of quadruplicate wells and the ± s.d. is represented by error bars.