Skip to main content
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1991 Aug;44(8):697–698. doi: 10.1136/jcp.44.8.697

Detection of Helicobacter pylori carriers by discriminant analysis of urea and pH levels in gastric juices.

F Ameglio 1, M R Abbolito 1, D Giannarelli 1, F Citarda 1, A Grassi 1, G M Gandolfo 1, V Casale 1
PMCID: PMC496772  PMID: 1890208

Abstract

An alternative approach to the problems inherent in current methods for detecting Helicobacter pylori carriers--that of being generally time-consuming, expensive, and not sufficiently sensitive--was devised by using the urea concentration and pH levels of gastric juices. A linear discriminant analysis of these variables, measured in 54 patients submitted to digestive endoscopy for gastritis, provided a mathematical formula for assigning the subjects (previously classified by other standard methods) to groups of either positive or negative H pylori carriers. The results obtained showed a correct classification in 52 out of 54 cases with only one false negative and one false positive case.

Full text

PDF
697

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Marshall B. J., Langton S. R. Urea hydrolysis in patients with Campylobacter pyloridis infection. Lancet. 1986 Apr 26;1(8487):965–966. doi: 10.1016/s0140-6736(86)91060-3. [DOI] [PubMed] [Google Scholar]
  2. Rauws E. A., Langenberg W., Houthoff H. J., Zanen H. C., Tytgat G. N. Campylobacter pyloridis-associated chronic active antral gastritis. A prospective study of its prevalence and the effects of antibacterial and antiulcer treatment. Gastroenterology. 1988 Jan;94(1):33–40. [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES