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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Synlett. 2016 Jun;27(9):1310–1317. doi: 10.1055/s-0035-1561363

Scheme 2.

Scheme 2

Proposed equilibrium leading to activation of benzaldehyde for nucleophilic attack based on q measurements. Adapted with permission from Mei, Y.; Dissanayake, P.; Allen, M. J. J. Am. Chem. Soc. 2010, 12871. Copyright 2010 American Chemical Society