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. Author manuscript; available in PMC: 2016 Oct 5.
Published in final edited form as: Leukemia. 2016 Apr 5;30(8):1682–1690. doi: 10.1038/leu.2016.70

Fig. 1. BMI1 downregulation inhibits colony formation of Ph+ ALL primary cells.

Fig. 1

(A) BMI1 levels in ALL# 674 cells transduced with the shBMI1 #1 lentivirus; (B) methylcellulose colony formation (mean + SD of four independent experiments) of untreated or Doxy-treated (2.5μg/ml) parental, shBMI1#1- or shBMI1#2-transduced peripheral blood (n=2) or bone marrow (n=2) derived Ph+ ALL cells. Colonies were counted 10 days after seeding 4 × 104 cells/plate.