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The Journal of Biological Chemistry logoLink to The Journal of Biological Chemistry
. 2016 Aug 5;291(32):16923. doi: 10.1074/jbc.A110.172767

Gossypol induces death receptor-5 through activation of ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL.

Bokyung Sung, Jayaraj Ravindran, Sahdeo Prasad, Manoj K Pandey, Bharat B Aggarwal
PMCID: PMC4974406  PMID: 27496964

VOLUME 285 (2010) PAGES 35418–35427

This article has been retracted by the publisher. An investigation at MD Anderson determined that image of control HCT116 cells treated with TRAIL and the image of cells transfected with CHOP siRNA and treated with TRAIL in Fig. 5C were reused. Additionally, the Journal determined that the actin immunoblot in Fig. 2A was reused as the actin immunoblot in Fig. 3B; the control/TRAIL treated image had been reused in the DR5/Gossypol+TRAIL and in the scrambled siRNA/TRAIL images in Fig. 4B; the scrambled siRNA/Gossypol image from Fig. 4B was reused as the NAC image in Fig. 7C; and the control/Gossypol image was reused as the CHOP siRNA/medium in Fig. 5C.


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